NABP NAPLEX Exam - Topic 7 Question 15 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 15
Topic #: 7

In a study where Rivaroxaban was compared to Enoxaparin to find total VTE following HIP replacement surgery, there were 17 total VTE out of 1513 patients in the Rivaraoaban group and 57 total VTE out of 1473 patient in the enoxaparin group.

What is the absolute risk reduction of using Rivaroxaban over Enoxaparin?

A17

B57

C71

D2.7

E0.27

Show Suggested Answer

Suggested Answer: D

Absolute risk reduction: 0.027 = 2.7% (Event rate in enoxaparin group) -- (Event rate in rivaroxaban group) = (57/1473) -- (17/1513) = 0.02746

by Kaitlyn at May 06, 2022, 11:20 AM

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Leonor

4 months ago

Absolute risk reduction is 2.7%!

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Oliva

4 months ago

Wait, how do we know these numbers are accurate?

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Huey

4 months ago

So, Rivaroxaban is definitely better here!

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Carin

4 months ago

Enoxaparin had 57 VTE out of 1473.

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Tonja

5 months ago

Rivaroxaban had 17 VTE out of 1513 patients.

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Joni

5 months ago

I think the answer might be D, 2.7, but I’m not confident. I remember we practiced calculating risk reductions, but this one feels a bit tricky.

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Blythe

5 months ago

I remember a similar question where we had to find the difference in VTE rates. If I recall correctly, we need to find the rates first before calculating the reduction.

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Salley

5 months ago

I think the absolute risk reduction is calculated by subtracting the event rates, but I'm not entirely sure how to do that with these numbers.

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Bulah

5 months ago

I feel like I might be mixing up the terms here. Is the absolute risk reduction just the difference in the number of events, or do we need to consider the total number of patients too?

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Terry

5 months ago

This question seems straightforward, I think the answer is B - adding both authors as impersonators of each other.

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Lauran

5 months ago

Hmm, I'm a bit unsure about this one. The question mentions agents being trained in one or two of the new support methods, so I'm not sure if a solution that covers all the channels would be the best approach.

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