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NABP NAPLEX Exam - Topic 6 Question 110 Discussion

Posted by Carla on Aug 16, 2025 at 04:04 AM

Which of the following would be most appropriate to treat infections associated with stenotrophomonas maltophilia?

Suggested Answer: D

Primary treatment for stenotrophomonas maltophilia is SMX-TMP. Meropenem, ciprofloxacin, Ampicillin and vancomycin have no coverage.


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14 comments · newest first
JE
Jesus 10 months ago
Vancomycin won't work for this, just FYI!
RO
Rozella 10 months ago
Really? I didn't know that, sounds surprising!
MO
Mozell 10 months ago
I thought meropenem was effective too?
DA
Dacia 10 months ago
Totally agree, it's one of the few effective options!
CO
Corrie 10 months ago
Sulfamethoxazole/trimethoprim is usually the go-to for S. maltophilia.
HU
Hubert 11 months ago
I have a vague memory that vancomycin wouldn't work here since it's more for Gram-positive infections. I think I should lean towards sulfamethoxazole/trimethoprim.
LA
Lauryn 11 months ago
I practiced a question similar to this, and I think ciprofloxacin was mentioned as an option, but I don't recall it being the best choice for this specific infection.
SH
Sheridan 11 months ago
I’m not entirely sure, but I feel like meropenem is not effective against this organism. I might be mixing it up with other Gram-negative bacteria.
MA
Mattie 11 months ago
I think I remember that Stenotrophomonas maltophilia is often resistant to many antibiotics, but isn't sulfamethoxazole/trimethoprim usually the go-to treatment?
IL
Ilda 12 months ago
I'm pretty confident on this one. Stenotrophomonas is an opportunistic pathogen that can cause serious infections, especially in immunocompromised patients. The treatment of choice is typically sulfamethoxazole/trimethoprim, so I'll select option D.
CO
Cordelia 12 months ago
Wait, is Stenotrophomonas the same as Pseudomonas? I'm getting a bit mixed up here. Maybe I should review my notes on gram-negative bacteria before answering this.
MI
Michell 12 months ago
Okay, I've got this. Stenotrophomonas is often resistant to many common antibiotics, but sulfamethoxazole/trimethoprim and fluoroquinolones like ciprofloxacin are usually good choices. I'll go with option D.
FL
Florinda 1 year ago
Hmm, I'm a bit unsure about this one. I know Stenotrophomonas can be tricky to treat, but I can't quite remember the preferred antibiotic options off the top of my head. I'll have to think this through carefully.
KA
Kati 1 year ago
This seems like a straightforward question about antibiotic treatment for Stenotrophomonas maltophilia infections. I'll need to recall what I know about the typical susceptibility patterns for this organism.
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