NABP NAPLEX Exam - Topic 4 Question 72 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 72
Topic #: 4

A 7-year-old boy has been suffering from influenza and had been given a drug by his father to decrease his high fever. A few hours later, his father brought him to the emergency room in a comatose state with a papulovesicular rash all over the body, moderate hepatomegaly, and asterixis. Laboratory studies reveal elevated levels of blood ammonia, AST, ALT, and PT. CT scan findings are suggestive for generalized cerebral edema.

The drug the father gave his son is most likely which of the following drugs?

AAspirin

BAcetaminophen

CIndomethacin

DMefenamic acid

EDiclofenac

Show Suggested Answer

Suggested Answer: D

Pregabalin is the active ingredient of the medicine Lyrica; a drug used to treat epilepsy, neuropathic pain, fibromyalgia and generalized anxiety disorder (GAD).

by Glenn at Dec 08, 2023, 12:46 PM

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Gwenn

3 months ago

Wow, didn't know aspirin could cause that!

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Diane

3 months ago

I thought acetaminophen was safe for kids?

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Salome

3 months ago

Wait, are we sure it's not acetaminophen?

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Hubert

4 months ago

Definitely aspirin! Classic case.

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Silvana

4 months ago

Sounds like Reye's syndrome, so probably aspirin.

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Tamesha

4 months ago

I feel like I read something about indomethacin and its side effects, but I don’t recall it being linked to this kind of presentation.

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Nana

4 months ago

This case reminds me of a practice question about drug toxicity. I think aspirin is the most likely culprit given the rash and liver issues.

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Mozell

4 months ago

I'm not entirely sure, but I think acetaminophen is usually safe for kids, right? The symptoms seem more severe for that option.

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Micheline

5 months ago

I remember learning that aspirin can cause Reye's syndrome in children with viral infections, which fits the symptoms here.

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Gladys

5 months ago

I've got a good feeling about this. The combination of sympJunita and lab abnormalities points pretty clearly to one of the options. I'm confident I can get this right.

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Chan

5 months ago

Yikes, this is a tough one. The cerebral edema and coagulopathy really complicate things. I'll have to use my best clinical reasoning to nail down the culprit drug.

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Starr

5 months ago

Okay, let's think this through step-by-step. The key clues seem to be the altered mental status and hepatic involvement. I'll weigh the options carefully.

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Junita

5 months ago

Hmm, the coma, rash, and elevated liver enzymes are concerning. I'm going to review my pharmacology notes to see which drug could cause this presentation.

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Emogene

5 months ago

This sounds like a tricky case. I'll need to carefully consider the symptoms and lab findings to determine the most likely drug.

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Rolland

5 months ago

I think the webinar format would be most effective for a large online audience. It allows the presenter to share information and visuals with everyone at once.

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Earleen

5 months ago

This one seems pretty straightforward. The statement of cash flows covers the key business activities - operating, investing, and financing. I'm confident I can get this one right.

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Gerri

5 months ago

I can't quite recall how the nature and age of assets factor into this. Was that a specific focus in our studies?

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Ashlyn

5 months ago

Hmm, I'm not sure about the difference between "Tab Color" and "Sheet Color" options. I'll have to read the question carefully.

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Fernanda

10 months ago

Oof, this one's a real head-scratcher. Maybe the dad was feeling a little 'mefenamic' and grabbed the wrong meds. D, just for the pun-tastic possibilities.

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Mary

8 months ago

A: Definitely. I wonder if he realized his error too late.

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Brinda

9 months ago

B: Yeah, it's really sad. I think the dad made a mistake with the medication.

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Long

9 months ago

A: That's a tough situation. I hope the boy will be okay.

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Brittney

10 months ago

Ah, the old 'Which potentially toxic drug did the parent accidentally give the kid?' trick question. I'm going to have to go with my gut on this one - B, acetaminophen. Dad's probably feeling pretty guilty right about now.

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Octavio

10 months ago

Hold up, what if the dad was just really confused and gave the kid some random NSAID like indomethacin or diclofenac? Tricky question, but I'll go with C or E just to be safe.

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Lashonda

9 months ago

Yeah, let's go with option E) Diclofenac just to be on the safe side.

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Justine

9 months ago

I agree, option E) Diclofenac seems like a possible culprit.

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Margot

9 months ago

I think it's safer to go with option E) Diclofenac.

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Thaddeus

10 months ago

No way, it's gotta be acetaminophen! That's the go-to fever reducer for kids, and the side effects match up perfectly. B is the answer, for sure.

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Jeannine

10 months ago

Hmm, this sounds like a classic case of aspirin toxicity. The symptoms are spot on - coma, rash, liver issues, and cerebral edema. I'm going with A, aspirin.

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