NABP NAPLEX Exam - Topic 3 Question 9 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 9
Topic #: 3

[All NAPLEX Questions]

How does pregabalin work in the treatment of seizures?

ASodium channel blocker

B2 ligand

CAMPA receptor antagonist

DGABA agonist

ESV2A binder

Show Suggested Answer

Suggested Answer: B

Pregabalin works as a ligand of the auxiliary 2 subunit site of certain voltage-dependent calcium channels (VDCCs), and thereby acts as an inhibitor of 2 subunit-containing VDCCs.

by Rima at May 07, 2022, 10:28 PM

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Samira

4 months ago

Really? I had no idea it worked like that!

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Dalene

4 months ago

I thought it was an AMPA receptor antagonist?

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Wai

4 months ago

Wait, isn't it also involved with GABA?

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Ryann

4 months ago

Totally agree, it's not a sodium channel blocker!

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Lindsey

5 months ago

Pregabalin is a 2 ligand, right?

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Lenita

5 months ago

I thought pregabalin was more about GABA modulation, but now I'm questioning if it's really a GABA agonist or something different.

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Jeff

5 months ago

I feel like there was a question about AMPA receptors in our practice tests, but I don't think pregabalin works that way.

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Karan

5 months ago

I remember studying that pregabalin binds to the 2 ligand, but I can't recall if that's the main mechanism for seizures.

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Dorothea

5 months ago

I think pregabalin is related to calcium channels, but I'm not sure if it's a sodium channel blocker or something else.

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Mable

5 months ago

I'm a bit confused by the different options here. I'll need to really analyze the code and the descriptions to determine which one is the correct approach for dealing with the rate limiting problem.

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Moon

5 months ago

Ah, the GECOS field - I remember learning about that in my Linux administration class. I'm pretty confident I can narrow this down.

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Tamra

5 months ago

This looks straightforward. I'll just need to set up the cron job with the correct time and command.

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