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How does pregabalin work in the treatment of seizures?
Suggested Answer: B
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Pregabalin works as a ligand of the auxiliary 2 subunit site of certain voltage-dependent calcium channels (VDCCs), and thereby acts as an inhibitor of 2 subunit-containing VDCCs.
12 comments · newest first
SA
Samira
11 months ago
Really? I had no idea it worked like that!
DA
Dalene
12 months ago
I thought it was an AMPA receptor antagonist?
WA
Wai
12 months ago
Wait, isn't it also involved with GABA?
RY
Ryann
12 months ago
Totally agree, it's not a sodium channel blocker!
LI
Lindsey
1 year ago
Pregabalin is a 2 ligand, right?
LE
Lenita
1 year ago
I thought pregabalin was more about GABA modulation, but now I'm questioning if it's really a GABA agonist or something different.
JE
Jeff
1 year ago
I feel like there was a question about AMPA receptors in our practice tests, but I don't think pregabalin works that way.
KA
Karan
1 year ago
I remember studying that pregabalin binds to the 2 ligand, but I can't recall if that's the main mechanism for seizures.
DO
Dorothea
1 year ago
I think pregabalin is related to calcium channels, but I'm not sure if it's a sodium channel blocker or something else.
MA
Mable
1 year ago
I'm a bit confused by the different options here. I'll need to really analyze the code and the descriptions to determine which one is the correct approach for dealing with the rate limiting problem.
MO
Moon
1 year ago
Ah, the GECOS field - I remember learning about that in my Linux administration class. I'm pretty confident I can narrow this down.
TA
Tamra
1 year ago
This looks straightforward. I'll just need to set up the cron job with the correct time and command.