NABP NAPLEX Exam - Topic 1 Question 113 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 113
Topic #: 1

JM is a 32-year-old women who comes to your diabetic clinic with complain of several episodes of hypoglycemi

a. She is on Insulin NPH/regular 70/30, 22 units twice a day with breakfast and dinner. 8 units with lunch.

After discussing with physician you decide to decrease the total daily insulin by 10% and change to insulin glargine once a day and Insulin Lispro three time a day at ratio of 50:50 -- 50 % of long and 50 % of short acting insulin.

What is her new insulin regimen? Round down to the nearest 1 unit.

A16 units of insulin glargine once daily, Insulin Lispro 4 units 3 times a day with meals

B15 units of insulin glargine once daily, Insulin Lispro 5 units 3 times a day with meals

C23 units of insulin glargine once daily, Insulin Lispro 7 units 3 times a day with meals

D30 units of insulin glargine once daily, Insulin Lispro 6 units 3 times a day with meals

E18 units of insulin glargine once daily, Insulin Lispro 6 units 3 times a day with meals

Show Suggested Answer

Suggested Answer: C

22 2 + 7 = 51 units of total insulin per day. Decrease by 10% 51 units 0.9 = 45.9 units per day round up to 46 units. 46 units 0.50 = 23 units, administer 23 units of insulin glargine once daily. 46 units 0.50 = 23 units total Insulin Lispro. Round down, divided by three times a day, 7 units 3 times a day with meals.

by Haydee at Nov 23, 2025, 12:48 AM

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Louann

12 hours ago

D) 30 units of insulin glargine once daily, Insulin Lispro 6 units 3 times a day with meals. Wait, is that too much insulin? I'm so confused.

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Roslyn

6 days ago

This question is making my head spin. I'll just go with C) and hope for the best.

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Donette

11 days ago

E) 18 units of insulin glargine once daily, Insulin Lispro 6 units 3 times a day with meals. Yep, that's the one.

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Quinn

16 days ago

A) 16 units of insulin glargine once daily, Insulin Lispro 4 units 3 times a day with meals. Looks good, but I'd round up to the nearest unit just to be safe.

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Lavera

21 days ago

B) 15 units of insulin glargine once daily, Insulin Lispro 5 units 3 times a day with meals. Seems like the right answer to me.

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Leonida

26 days ago

I feel like option B makes sense since it seems to balance the long and short-acting insulin, but I'm not entirely confident about the numbers.

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France

1 month ago

I practiced a similar question where we had to switch from NPH to glargine, but I can't recall the exact ratios we used for Lispro.

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Cory

1 month ago

I think the total daily insulin was 62 units before the change, so 10% would be about 6 units, right?

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German

1 month ago

I remember we talked about reducing the total daily insulin by 10%, but I'm not sure how to calculate that exactly.

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Lai

2 months ago

Okay, I think I've got a good strategy. I'll break this down into smaller steps, calculate the new total daily insulin, and then divide it up accordingly. Gotta stay focused and double-check my work.

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Kimberlie

2 months ago

Whoa, this is a lot of information to process. I better read through it carefully and make sure I understand all the details before I start calculating. Don't want to make any silly mistakes.

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Louvenia

2 months ago

Alright, I've got this. I just need to do the math step-by-step and make sure I'm rounding down to the nearest unit. I feel confident I can get the right answer.

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Christa

2 months ago

I think the answer is A. It seems reasonable.

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Blair

2 months ago

Wait, how did we get to 16 units for glargine? Seems off.

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Muriel

2 months ago

JM's total daily insulin was 66 units before the reduction.

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Tula

3 months ago

I think option A looks right based on the calculations!

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Flo

3 months ago

This question is a real insulin-ator. I'm going with E) just to see if I can get lucky.

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Lenna

3 months ago

Okay, let's see. I need to figure out the total daily insulin and then split it into the long-acting and short-acting components. This will take some thinking, but I think I can work it out.

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Lawrence

3 months ago

Hmm, this looks like a tricky one. I'll need to carefully calculate the new insulin regimen based on the 10% decrease and the 50:50 ratio.

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