Which technique would best assist the sonographer to verify the finding in this image obtained from the right upper quadrant?

The image demonstrates a gallbladder with a possible echogenic focus (likely a gallstone) and posterior acoustic shadowing. This is suggestive of cholelithiasis. To differentiate uncomplicated gallstones from acute cholecystitis, the most effective technique is to assess for a positive sonographic Murphy sign.
A positive sonographic Murphy sign refers to the presence of focal tenderness over the gallbladder when it is directly palpated with the ultrasound transducer. It is a strong indicator of acute cholecystitis when combined with other features such as gallbladder wall thickening, pericholecystic fluid, and gallstones.
Sonographic Murphy sign --- key points:
Assessed during real-time scanning
Localized tenderness when pressure is applied over the gallbladder
Highly sensitive for acute cholecystitis (especially in the presence of stones)
Differentiation from other options:
A . Use compound imaging: Improves image quality by reducing artifacts but does not verify tenderness or confirm acute inflammation.
B . Change the patient's position: Helpful to confirm mobility of gallstones, but not diagnostic of inflammation.
C . Ask patient to perform Valsalva: Used primarily in vascular studies (e.g., assessing for varicocele or venous reflux), not relevant here.
Rumack CM, Wilson SR, Charboneau JW, Levine D. Diagnostic Ultrasound. 5th Edition. Elsevier, 2018. Chapter: Gallbladder and Biliary System, pp. 148--152.
AIUM Practice Parameter for the Performance of an Ultrasound Examination of the Abdomen and/or Retroperitoneum, 2020.
Radiopaedia.org. Sonographic Murphy sign: https://radiopaedia.org/articles/sonographic-murphy-sign
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