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NABP FPGEE Exam - Topic 2 Question 85 Discussion

Actual exam question for NABP's FPGEE exam
Question #: 85
Topic #: 2
[All FPGEE Questions]

Mechanism of action of doxorubicin is:

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Suggested Answer: E

by Marge at Jun 28, 2024, 05:02 PM

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Louisa
6 months ago
I thought it had something to do with GABA... am I wrong?
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Haley
6 months ago
Definitely not an alpha or beta antagonist!
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Clay
6 months ago
Wait, isn't it also a DNA intercalator?
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Lashunda
7 months ago
Totally agree, that's the main action!
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Lindy
7 months ago
Doxorubicin inhibits topoisomerase II, right?
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Marti
7 months ago
I don't recall doxorubicin enhancing GABAergic inhibition, so that option seems unlikely to me.
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Antonio
7 months ago
I’m a bit confused; I thought doxorubicin had something to do with beta antagonism, but that might be another drug.
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Shawna
7 months ago
I remember practicing a question about cancer drugs, and I think doxorubicin was mentioned as a topoisomerase inhibitor.
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Kasandra
8 months ago
I think doxorubicin works by inhibiting topoisomerase II, but I'm not completely sure.
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Tamesha
8 months ago
Ah, I remember now! Doxorubicin's primary mechanism is inhibiting topoisomerase II, which is essential for DNA unwinding and replication. That's definitely the best answer here.
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Stephaine
8 months ago
Wait, I'm getting a bit confused here. Doxorubicin has multiple mechanisms, right? I think it might also have some alpha or beta antagonist activity. I'll have to review my notes to be sure.
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Ira
8 months ago
Okay, let me see. Doxorubicin is an anthracycline antibiotic, so it likely interferes with DNA replication or transcription. I'm going to go with option A, inhibiting topoisomerase II.
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Hyman
8 months ago
Hmm, I'm a bit unsure about this one. I know doxorubicin is an antineoplastic agent, but I can't quite remember the specific mechanism. I'll have to think this through carefully.
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Val
8 months ago
I'm pretty confident that the mechanism of action of doxorubicin is inhibiting topoisomerase II, so I'll go with option A.
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Gladis
8 months ago
I think this question is asking about the section of the TOGAF document that covers the processes, skills, and roles needed to establish and operate an architecture function within an enterprise. Based on that, my best guess is that the answer is Part VII: Architecture Capability Framework.
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Gertude
8 months ago
Okay, I've got it! The policy dataset defines the IP addresses that are part of the "Admin_group". Then the responder policy "POL_1" blocks any traffic that doesn't come from those IP addresses. So option A is the correct answer.
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Eun
1 year ago
Wait, doxorubicin is an alpha blocker? That's just ridiculous. I'm going to have to go with the classic topoisomerase II inhibitor, A.
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Belen
1 year ago
I've also heard that doxorubicin works by inhibiting topoisomerase II. It's a well-known mechanism for this drug.
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Marge
1 year ago
Yeah, A is the correct answer. It's a common mechanism of action for doxorubicin.
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Lashandra
1 year ago
I agree, doxorubicin is definitely not an alpha blocker. Topoisomerase II inhibition makes more sense.
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Catarina
1 year ago
Hmm, allosterically enhancing GABA? That's just silly. This is clearly a cancer drug, not a central nervous system one. A has got to be the right answer here.
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Mona
1 year ago
Haha, beta antagonist? What is this, a cardiovascular exam? Definitely not D. I'm going to go with the topoisomerase II option, A.
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Audrie
12 months ago
Good choice, A is the correct answer for the mechanism of action of doxorubicin.
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Mel
12 months ago
Definitely not D, that's for sure. A is the right choice.
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Marlon
1 year ago
Yeah, that's right. Doxorubicin works by inhibiting topoisomerase II.
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Kimbery
1 year ago
I think A is correct, it inhibits topoisomerase II.
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Chun
1 year ago
Wait, isn't doxorubicin an antitumor antibiotic? I think it's got to be something related to DNA or protein synthesis. C - inhibits peptidyl transferase seems more plausible.
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Lashandra
1 year ago
Doxorubicin is a chemotherapy drug, so it's got to be inhibiting something important for cancer cells. I'm going with A - inhibits topoisomerase II. Sounds like the right mechanism to me.
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Dick
12 months ago
User4: Yeah, A) makes sense for a drug like doxorubicin
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Noelia
1 year ago
User3: I'm not sure, but I'll go with A) too
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Wilburn
1 year ago
User2: I agree, that seems like the right mechanism for a chemotherapy drug
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Sherell
1 year ago
User 2: Yeah, that makes sense for a chemotherapy drug.
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Annice
1 year ago
User 1: I think it inhibits topoisomerase II.
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Justine
1 year ago
User1: I think it's A) Inhibits topoisomerase II
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Nickolas
1 year ago
I'm not sure, but I think the correct answer is A) Inhibits topoisomerase II based on what I've studied.
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Steffanie
1 year ago
I agree with Jenelle, because doxorubicin is known to inhibit topoisomerase II which leads to DNA damage.
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Jenelle
1 year ago
I think the mechanism of action of doxorubicin is A) Inhibits topoisomerase II.
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