Utilizing AWS Config with a custom AWS Config rule (ec2-managedinstance-applications-required) enables detection of EC2 instances lacking the required software across all accounts in an organization. By creating an Amazon EventBridge rule that triggers on AWS Config events, and configuring it to invoke an AWS Lambda function, automated actions can be taken to ensure compliance. The Lambda function can leverage AWS Systems Manager Run Command to install the necessary software on non-compliant instances. This approach ensures continuous compliance and automated remediation, aligning with best practices for cloud security and management.