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PTCB PTCE Exam - Topic 4 Question 125 Discussion

Posted by Ronnie on May 07, 2026 at 02:42 AM

A patient is prescribed Prilosec capsules for gastroesophageal reflux disease. If thepatient is unable to swallow capsules, they may:

Suggested Answer: A

Prilosec (Omeprazole) is a delayed-release proton pump inhibitor (PPI)used forGERD, ulcers, and acid reflux. It comes incapsulescontainingenteric-coated granules, designed to protect the medication from stomach acid and ensure proper absorption.

Prilosec capsules contain enteric-coated granulesthat are safe to sprinkle on soft foodswithout chewing.

Applesauce is an ideal optionbecause it doesnot interfere with drug absorption or stability.

B . Chew and swallow the capsules Incorrect

Chewing destroys the enteric coating, leading to premature drug release and degradation by stomach acid.

C . Compound the capsules into a topical preparation Incorrect

Prilosecis not formulated for topical use. The medication must reach the stomach intact for proper effect.

D . Allow the capsules to dissolve under the tongue Incorrect

Sublingual administration is ineffectivebecauseomeprazole is not absorbed through the mucous membranesand needs enteric protection.

FDA Omeprazole Medication Guide-- States that the contents can be sprinkled on applesauce.

ISMP Safe Medication Use Guidelines-- Emphasizes proper administration of delayed-release capsules.

PTCB PTCE Exam Content Outline-- Covers modified-release formulations and proper drug administration techniques.

Why Can the Capsules Be Opened?Why Not the Other Options?Key Reference:


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24 comments · newest first
TR
Tracie 2 days ago
C is out of the question. Topical won't work for this.
PE
Percy 7 days ago
Plus, it helps with taste masking too.
SH
Sheron 12 days ago
Exactly! A is the only logical choice here.
JO
Jolanda 17 days ago
Right, and D seems risky. Not meant for sublingual use.
TR
Tracie 23 days ago
B is not a good idea. Chewing could alter the medication.
PE
Percy 28 days ago
I agree, A makes sense. It’s safe and effective.
SH
Sheron 1 month ago
I think A is the best option. Applesauce is easy to swallow.
AM
Amie 1 month ago
Plus, applesauce masks the taste.
DA
Dana 1 month ago
Exactly! A is the most practical choice.
LE
Lemuel 2 months ago
D sounds strange. It won't work properly that way.
NA
Nana 2 months ago
C is not appropriate. It’s not meant for topical use.
EL
Eleonore 2 months ago
Right, we need to avoid that. A is safe and effective.
AM
Amie 2 months ago
Option B is risky. Chewing could alter the medication.
KE
Kenneth 2 months ago
Agreed! Capsules can be hard to swallow.
DA
Dana 2 months ago
I think A is the best option. Applesauce makes it easier to take.
PR
Providencia 3 months ago
I’m surprised they allow that! I always thought it had to stay intact.
HU
Huey 3 months ago
Chewing the capsules? That's definitely a bad idea!
JA
Jacki 3 months ago
Wait, can you really open capsules? I thought that was a no-go.
GE
Geraldine 3 months ago
Totally agree, that's what my doctor said too!
EL
Elliott 3 months ago
A) is correct! You can sprinkle it on applesauce.
LU
Ludivina 4 months ago
I don't recall any option about topical preparations for oral medications. That seems off to me.
MO
Mozell 5 months ago
I practiced a question similar to this, and I believe the right answer is to sprinkle the contents on something soft, like applesauce.
BR
Brock 5 months ago
I'm not entirely sure, but I feel like chewing the capsules isn't a good idea. I think it could affect how the medication works.
HE
Herminia 5 months ago
I think I remember something about opening capsules and mixing them with food, like applesauce. That sounds familiar.
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