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PTCB PTCE Exam Questions
- Topic 1: Medications: This section measures the skills of Pharmacy Technicians and covers knowledge of generic and brand names, classifications, therapeutic equivalence, drug interactions, contraindications, strengths, dosage forms, administration routes, side effects, indications, drug stability, narrow therapeutic index medications, incompatibilities, and proper storage1246. It requires a comprehensive understanding of medication properties and handling.
- Topic 2: Federal Requirements: This section assesses the competencies of Pharmacy Managers in federal laws and regulations related to handling and disposal of substances, controlled substance prescriptions, restricted drug programs, and FDA recall requirements12. It emphasizes compliance and regulatory expertise.
- Topic 3: Patient Safety and Quality Assurance: This section measures the skills of Pharmacy Technicians and covers high-alert medications, error prevention strategies, issues requiring pharmacist intervention, event reporting, prescription error types, and hygiene standards12. It focuses on safe pharmacy practices and error handling.
- Topic 4: Order Entry and Processing: This section measures the skills of Pharmacy Technicians and assesses procedures for compounding non-sterile products, calculations, ratios, proportions, conversions, Sig codes, abbreviations, medical terminology, administration equipment, lot numbers, expiration dates, NDC numbers, and procedures for handling medications and supplies12. It emphasizes accuracy and efficiency in prescription processing.
Free PTCB PTCE Exam Actual Questions
Note: Premium Questions for PTCE were last updated On Mar. 10, 2026 (see below)
Ahazardous drug spill kitfor pharmacy use should include:
Comprehensive and Detailed Step-by-Step Explanation:
Ahazardous drug spill kitisrequiredunderUSP <800>, which outlinessafe handling practices for hazardous drugs (HDs). The kit must contain:
Disposable scoop and scraper(to safely collect broken glass and contaminated material).
Absorbent pads or spill control pillows(for liquid spills).
Chemotherapy-rated gloves, gown, goggles, and mask(for protection).
A hazardous waste disposal bag(to properly dispose of contaminated materials).
Explanation of Answer Choices:D. A disposable scoop for glass fragmentsCorrect.Adisposable scoop is essentialto safely removehazardous drug spills containing broken glass.A. Permeable, disposable protective garments Incorrect. PPE for hazardous drug spills must beimpermeable(e.g., coated gowns).B. Sufficient supplies to absorb a spill of about 10,000 mL Incorrect.Most spill kits are designed for smaller spills (1000 mL), not massive industrial spills.C. Reusable absorbent sponges or toweling Incorrect.All absorbent materials must be disposable to prevent contamination.
Reference:
USP <800>: Handling Hazardous Drugs in Healthcare Settings
NIOSH List of Hazardous Drugs (2020 Update)
PTCB Exam: Medication Safety & Hazardous Drug Management
According tofederal law, a prescription for which of the following medicationsmay be transferredto another pharmacy to be refilled?
Comprehensive and Detailed Step-by-Step Explanation:
Underfederal law (21 CFR 1306.25),Schedule III-V controlled substances (e.g., Alprazolam)can be transferred ONCEfor refill purposes between licensed pharmacieswith a shared database.Schedule II drugs (e.g., Methylphenidate, Fentanyl, Hydromorphone) CANNOT be transferred.
Explanation of Answer Choices:A. Alprazolam (C-IV)Correct.Schedule III-V drugs can be transferred ONCEfor refill purposes.B. Methylphenidate (C-II) Incorrect.Schedule II drugs cannot be transferred.C. Fentanyl (C-II) Incorrect.C-II drugs are non-transferablebetween pharmacies.D. Hydromorphone (C-II) Incorrect.C-II drugs cannot be transferred.
Reference:
DEA Controlled Substance Act (CSA)
21 CFR 1306.25 -- Prescription Transfers
According to the Institute for Safe Medication Practices (ISMP), which of the following is an approved abbreviation?
TheInstitute for Safe Medication Practices (ISMP)maintains a list oferror-prone abbreviationsthat shouldnot be usedin medication orders to prevent misinterpretation and medication errors.
Analysis of the Answer Choices:Abbreviation
Meaning
ISMP Recommendation
U
Units
Do NOT use Can be mistaken for '0' or '4' (e.g., 10U could be misread as 100).Use'unit'instead.
AD
Right ear
Do NOT use Can be confused with 'OD' (right eye).Use'right ear'instead.
AU
Both ears
Do NOT use Can be confused with 'OU' (both eyes).Use'both ears'instead.
gtt
Drop
Accepted Common and not considered error-prone.
Since'gtt' for drop is not on ISMP's 'Do Not Use' list, it is the correct answer.
ISMP List of Error-Prone Abbreviations-- Confirms that 'U,' 'AD,' and 'AU' should not be used in prescriptions.
Joint Commission 'Do Not Use' List-- Prohibits 'U' and similar abbreviations to prevent dosing errors.
PTCB PTCE Exam Content Outline-- Covers error prevention strategies, including abbreviation safety.
Key Reference:
Famotidine oral suspensionremains stable for a maximum of how many days following reconstitution?
Famotidine suspension is stable for 21 days when stored in the refrigerator (2C--8C or 36F--46F).
Reference:FDA Famotidine Stability Guidelines, USP Storage Guidelines.
A prescription calls foramoxicillin 500 mg PO t.i.d.Which of the following must be provided by the prescriber in order for the prescription to be filled?
Therapy duration (length of treatment)must be specified, especially forantibiotics, to ensureappropriate treatment completion and prevent antibiotic resistance.
Typical duration for amoxicillin:
7--10 days for infections
5 days for strep throat
Reference:CDC Antibiotic Prescribing Guidelines, PTCE Prescription Requirements.
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