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PTCB PTCE Exam Questions
- Topic 1: Medications: This section measures the skills of Pharmacy Technicians and covers knowledge of generic and brand names, classifications, therapeutic equivalence, drug interactions, contraindications, strengths, dosage forms, administration routes, side effects, indications, drug stability, narrow therapeutic index medications, incompatibilities, and proper storage1246. It requires a comprehensive understanding of medication properties and handling.
- Topic 2: Federal Requirements: This section assesses the competencies of Pharmacy Managers in federal laws and regulations related to handling and disposal of substances, controlled substance prescriptions, restricted drug programs, and FDA recall requirements12. It emphasizes compliance and regulatory expertise.
- Topic 3: Patient Safety and Quality Assurance: This section measures the skills of Pharmacy Technicians and covers high-alert medications, error prevention strategies, issues requiring pharmacist intervention, event reporting, prescription error types, and hygiene standards12. It focuses on safe pharmacy practices and error handling.
- Topic 4: Order Entry and Processing: This section measures the skills of Pharmacy Technicians and assesses procedures for compounding non-sterile products, calculations, ratios, proportions, conversions, Sig codes, abbreviations, medical terminology, administration equipment, lot numbers, expiration dates, NDC numbers, and procedures for handling medications and supplies12. It emphasizes accuracy and efficiency in prescription processing.
Free PTCB PTCE Exam Actual Questions
Note: Premium Questions for PTCE were last updated On Jul. 24, 2025 (see below)
Which of the following auxiliary labels would be most appropriate to affix to a bottle ofcephalexin oral suspensionafter reconstitution?
Comprehensive and Detailed Step-by-Step Explanation:
Cephalexin suspension (Keflex)is anantibioticthat must berefrigerated after reconstitutionanddiscarded after 14 daysto maintain stability and potency.
Explanation of Answer Choices:D. Keep refrigerated; Discard after 14 daysCorrect.Proper storage is2-8C (36-46F), with a 14-day shelf life.A. Protect from light; Discard after 7 days Incorrect.Refrigeration is required, not just light protection.B. Protect from light; Discard after 14 days Incorrect.Light protection is not a major concern for cephalexin.C. Keep refrigerated; Discard after 7 days Incorrect.Cephalexin is stable for 14 days, not just 7.
Reference:
USP <795>: Beyond-Use Dating for Reconstituted Suspensions
FDA Drug Stability Guidelines
A local provider has written the following compounded prescription for a patient:
Zinc oxide ointment 20% 60 g
Nystatin ointment 100,000 units/g 60 g
Hydrocortisone ointment 1% 60 g
Cholestyramine powder 10 g
Mineral oil USP 10 mL
Total Weight 200 g
Which of the agents listed is an antifungal agent?
In the providedcompounded prescription, the antifungal agent isnystatin.
Nystatin is a polyene antifungalthat works by binding toergosterolin fungal cell membranes, causing leakage of cellular contents and fungal cell death.
It iscommonly used for fungal infections, particularlycutaneous or mucosal Candida infections(e.g., diaper rash, oral thrush).
A . Cholestyramine. Incorrect. Cholestyramine is abile acid sequestrantused to lowercholesteroland treatdiarrhea(often in combination with other ingredients for skin irritation or wounds).
B . Hydrocortisone. Incorrect. Hydrocortisone is acorticosteroidused to reduceinflammation and itching, but it does not kill fungi.
C . Zinc oxide. Incorrect. Zinc oxide is askin protectantused fordiaper rash and minor burns, but it is not an antifungal.
Lexicomp Drug Database -- Nystatin Mechanism of Action.
FDA Drug Label for Nystatin -- Antifungal Properties.
PTCB PTCE Exam Content Outline -- Compounded Preparations and Active Ingredients.
Mosby's Pharmacy Technician: Principles and Practice -- Dermatologic Compounding.
Why Is Nystatin an Antifungal?Why the Other Answer Choices Are Incorrect:Pharmacy Technician Reference:Conclusion:Pharmacy technicians must befamiliar with drug classificationsto correctly identify active ingredients incompounded prescriptions.Nystatin is the only antifungal agentin the provided formulation.
The generic name for which of the following medications is paired with oxaprozin on the list of confused drug names?
Oxaprozinis anonsteroidal anti-inflammatory drug (NSAID)used to treat arthritis. It is listed on theISMP (Institute for Safe Medication Practices) List of Confused Drug Namesdue to its similarity toTopamax (topiramate), an anticonvulsant used for epilepsy and migraine prevention. The confusion arises because both drug nameslook and sound similar, which can lead to dispensing errors.
A . Tobradex Incorrect. Tobradex is anantibiotic/steroid ophthalmic medicationand is not confused with oxaprozin.
C . Tradjenta Incorrect. Tradjenta (linagliptin) is aDPP-4 inhibitor for diabetesand is not commonly confused with oxaprozin.
D . Trileptal Incorrect. Trileptal (oxcarbazepine) is ananticonvulsantbut is not on the ISMP Confused Drug List with oxaprozin.
Incorrect Answer Choices:Pharmacy Technician Reference:
PTCB PTCE Exam Content Outline (Error Prevention and Look-Alike/Sound-Alike (LASA) Drugs)
Institute for Safe Medication Practices (ISMP) List of Confused Drug Names
FDA Drug Safety Communications
Mosby's Pharmacy Technician Exam Review
According tofederal law, a prescription for which of the following medicationsmay be transferredto another pharmacy to be refilled?
Comprehensive and Detailed Step-by-Step Explanation:
Underfederal law (21 CFR 1306.25),Schedule III-V controlled substances (e.g., Alprazolam)can be transferred ONCEfor refill purposes between licensed pharmacieswith a shared database.Schedule II drugs (e.g., Methylphenidate, Fentanyl, Hydromorphone) CANNOT be transferred.
Explanation of Answer Choices:A. Alprazolam (C-IV)Correct.Schedule III-V drugs can be transferred ONCEfor refill purposes.B. Methylphenidate (C-II) Incorrect.Schedule II drugs cannot be transferred.C. Fentanyl (C-II) Incorrect.C-II drugs are non-transferablebetween pharmacies.D. Hydromorphone (C-II) Incorrect.C-II drugs cannot be transferred.
Reference:
DEA Controlled Substance Act (CSA)
21 CFR 1306.25 -- Prescription Transfers
Whichvitaminshould be takenbefore and during pregnancyto help avoidneural tube defects?
Folic acid (Vitamin B9) is crucial for fetal development, reducing the risk of neural tube defects like spina bifida.
Recommended dose: At least 400 mcg daily before pregnancy and during the first trimester.
Reference:CDC Folic Acid Pregnancy Guidelines, PTCE Vitamin & Supplement Guide.
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