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PTCB PTCE Exam - Topic 1 Question 114 Discussion

Actual exam question for PTCB's PTCE exam
Question #: 114
Topic #: 1
[All PTCE Questions]

Which of the following auxiliary labels would be most appropriate to affix to a bottle ofcephalexin oral suspensionafter reconstitution?

Show Suggested Answer Hide Answer
Suggested Answer: D

Comprehensive and Detailed Step-by-Step Explanation:

Cephalexin suspension (Keflex)is anantibioticthat must berefrigerated after reconstitutionanddiscarded after 14 daysto maintain stability and potency.

Explanation of Answer Choices:D. Keep refrigerated; Discard after 14 daysCorrect.Proper storage is2-8C (36-46F), with a 14-day shelf life.A. Protect from light; Discard after 7 days Incorrect.Refrigeration is required, not just light protection.B. Protect from light; Discard after 14 days Incorrect.Light protection is not a major concern for cephalexin.C. Keep refrigerated; Discard after 7 days Incorrect.Cephalexin is stable for 14 days, not just 7.

Reference:

USP <795>: Beyond-Use Dating for Reconstituted Suspensions

FDA Drug Stability Guidelines


Contribute your Thoughts:

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Erinn
2 months ago
Protect from light is important too, don’t forget that!
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Nobuko
2 months ago
Wait, are we sure about the 7 days? Seems short!
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Lonny
3 months ago
I thought it was 14 days for cephalexin?
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Matt
3 months ago
Definitely 7 days, I've seen it before.
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Domonique
3 months ago
Option C is correct, it needs refrigeration!
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Willis
3 months ago
I’m leaning towards option D, but I vaguely recall something about light sensitivity. I hope I’m not confusing it with another medication!
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My
4 months ago
I feel like I might have mixed up the discard times for different antibiotics. I need to double-check if cephalexin is 7 or 14 days.
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Mammie
4 months ago
I remember practicing a question like this, and I think the correct answer was to discard after 14 days. Protecting from light seems less relevant for this one.
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Dortha
4 months ago
I think cephalexin needs to be refrigerated after reconstitution, but I'm not sure about the discard time. Was it 7 or 14 days?
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Eden
4 months ago
I feel pretty confident about this one. Liquid oral suspensions generally need to be protected from light and have a shorter expiration date compared to solid dosage forms. So the best answer is option B - protect from light and discard after 14 days.
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Aileen
4 months ago
Okay, let's see. Cephalexin is an antibiotic, so it makes sense that it would need to be kept refrigerated to maintain potency. And a liquid formulation would probably have a shorter shelf life than tablets or capsules. I'm going to go with option C.
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Reta
4 months ago
Hmm, this is a tricky one. I'm not totally sure about the storage requirements for cephalexin suspension. I'll have to think it through carefully and review my notes before deciding.
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Desire
5 months ago
I think I know the answer to this one. Cephalexin oral suspension is a liquid medication, so it would need to be protected from light and have a shorter expiration date than a solid dosage form. I'm leaning towards option B.
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Gertude
5 months ago
I agree with Santos, I think C) Keep refrigerated; Discard after 7 days makes more sense for the stability of the medication.
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Peter
6 months ago
I'm not sure, but I think it's important to keep the medication refrigerated to maintain its effectiveness.
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Danilo
7 months ago
Option A sounds like the way to go. Protect it from light, and 7 days is just the right amount of time before it turns into a science experiment.
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Yolando
7 months ago
Haha, I bet the answer is D. Who doesn't love some extra fridge time and a longer shelf life? Cephalexin must be a hardy little antibiotic.
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Leonardo
5 months ago
User 3: Leonardo, I'm with you on this one. B seems like the best option.
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Frank
5 months ago
User 2: Frank, I disagree. I'm going with B for a longer shelf life.
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Sherron
6 months ago
User 1: I think the answer is A. Better safe than sorry with antibiotics.
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Novella
7 months ago
I disagree, I believe the correct answer is D) Keep refrigerated; Discard after 14 days.
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Lashanda
7 months ago
I'm going with C. Keeping it refrigerated is crucial, and 7 days is the standard for reconstituted suspensions, right?
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Daron
5 months ago
B) Protect from light; Discard after 14 days
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Kris
7 months ago
A) Protect from light; Discard after 7 days
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Santos
7 months ago
I think the answer is C) Keep refrigerated; Discard after 7 days.
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Arthur
7 months ago
Definitely B. Cephalexin oral suspension needs to be protected from light and can be stored for up to 14 days after reconstitution. Easy peasy!
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Georgene
7 months ago
Thanks for the info! I'll make sure to follow those instructions when reconstituting cephalexin oral suspension.
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Rebbeca
7 months ago
I agree, option B is the correct one. It's important to protect it from light and discard after 14 days.
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