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PTCB PTCE Exam - Topic 1 Question 114 Discussion

Posted by Brandon on Jul 13, 2025 at 10:30 PM

Which of the following auxiliary labels would be most appropriate to affix to a bottle ofcephalexin oral suspensionafter reconstitution?

Suggested Answer: D

Comprehensive and Detailed Step-by-Step Explanation:

Cephalexin suspension (Keflex)is anantibioticthat must berefrigerated after reconstitutionanddiscarded after 14 daysto maintain stability and potency.

Explanation of Answer Choices:D. Keep refrigerated; Discard after 14 daysCorrect.Proper storage is2-8C (36-46F), with a 14-day shelf life.A. Protect from light; Discard after 7 days Incorrect.Refrigeration is required, not just light protection.B. Protect from light; Discard after 14 days Incorrect.Light protection is not a major concern for cephalexin.C. Keep refrigerated; Discard after 7 days Incorrect.Cephalexin is stable for 14 days, not just 7.

Reference:

USP <795>: Beyond-Use Dating for Reconstituted Suspensions

FDA Drug Stability Guidelines


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28 comments · newest first
ER
Erinn 10 months ago
Protect from light is important too, don’t forget that!
NO
Nobuko 10 months ago
Wait, are we sure about the 7 days? Seems short!
LO
Lonny 10 months ago
I thought it was 14 days for cephalexin?
MA
Matt 10 months ago
Definitely 7 days, I've seen it before.
DO
Domonique 11 months ago
Option C is correct, it needs refrigeration!
WI
Willis 11 months ago
I’m leaning towards option D, but I vaguely recall something about light sensitivity. I hope I’m not confusing it with another medication!
MY
My 11 months ago
I feel like I might have mixed up the discard times for different antibiotics. I need to double-check if cephalexin is 7 or 14 days.
MA
Mammie 11 months ago
I remember practicing a question like this, and I think the correct answer was to discard after 14 days. Protecting from light seems less relevant for this one.
DO
Dortha 11 months ago
I think cephalexin needs to be refrigerated after reconstitution, but I'm not sure about the discard time. Was it 7 or 14 days?
ED
Eden 12 months ago
I feel pretty confident about this one. Liquid oral suspensions generally need to be protected from light and have a shorter expiration date compared to solid dosage forms. So the best answer is option B - protect from light and discard after 14 days.
AI
Aileen 12 months ago
Okay, let's see. Cephalexin is an antibiotic, so it makes sense that it would need to be kept refrigerated to maintain potency. And a liquid formulation would probably have a shorter shelf life than tablets or capsules. I'm going to go with option C.
RE
Reta 12 months ago
Hmm, this is a tricky one. I'm not totally sure about the storage requirements for cephalexin suspension. I'll have to think it through carefully and review my notes before deciding.
DE
Desire 1 year ago
I think I know the answer to this one. Cephalexin oral suspension is a liquid medication, so it would need to be protected from light and have a shorter expiration date than a solid dosage form. I'm leaning towards option B.
GE
Gertude 1 year ago
I agree with Santos, I think C) Keep refrigerated; Discard after 7 days makes more sense for the stability of the medication.
PE
Peter 1 year ago
I'm not sure, but I think it's important to keep the medication refrigerated to maintain its effectiveness.
DA
Danilo 1 year ago
Option A sounds like the way to go. Protect it from light, and 7 days is just the right amount of time before it turns into a science experiment.
YO
Yolando 1 year ago
Haha, I bet the answer is D. Who doesn't love some extra fridge time and a longer shelf life? Cephalexin must be a hardy little antibiotic.
LE
Leonardo 1 year ago
↳ replying to Yolando
User 3: Leonardo, I'm with you on this one. B seems like the best option.
FR
Frank 1 year ago
↳ replying to Yolando
User 2: Frank, I disagree. I'm going with B for a longer shelf life.
SH
Sherron 1 year ago
↳ replying to Yolando
User 1: I think the answer is A. Better safe than sorry with antibiotics.
NO
Novella 1 year ago
I disagree, I believe the correct answer is D) Keep refrigerated; Discard after 14 days.
LA
Lashanda 1 year ago
I'm going with C. Keeping it refrigerated is crucial, and 7 days is the standard for reconstituted suspensions, right?
DA
Daron 1 year ago
↳ replying to Lashanda
B) Protect from light; Discard after 14 days
KR
Kris 1 year ago
↳ replying to Lashanda
A) Protect from light; Discard after 7 days
SA
Santos 1 year ago
I think the answer is C) Keep refrigerated; Discard after 7 days.
AR
Arthur 1 year ago
Definitely B. Cephalexin oral suspension needs to be protected from light and can be stored for up to 14 days after reconstitution. Easy peasy!
GE
Georgene 1 year ago
↳ replying to Arthur
Thanks for the info! I'll make sure to follow those instructions when reconstituting cephalexin oral suspension.
RE
Rebbeca 1 year ago
↳ replying to Arthur
I agree, option B is the correct one. It's important to protect it from light and discard after 14 days.
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