According to the Agile Methodology1, the product owner is responsible for defining the product vision, managing the backlog, and ensuring that the development team is working on the right priorities. The product owner is also the primary customer advocate and the link between the business and technology strategy. Therefore, the product owner's engagement and interest are crucial for the success of the project. If the product owner changes during the project, the project manager should reevaluate the new product owner's needs, expectations, and communication preferences, and adjust the collaboration accordingly. This can help to avoid delays, misunderstandings, and conflicts, and ensure that the product owner is aligned with the project goals and the development team. The project manager should also facilitate the transition of the product owner role and ensure that the new product owner is familiar with the product vision, the backlog, and the agile principles and practices.Reference:

3: Agile Methodology: Role of Product Owners & Development Teams