NABP Exam NAPLEX Topic 9 Question 58 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 58
Topic #: 9

If a patient takes 0.5mg of intravenous hydromorphone every 4hrs what would be the equivalent orals total daily dose? Hydromorphone oral to parenteral ratio 7.5:1.5.

A15mg

B20mg

C10mg

D5mg

E7.5mg

Show Suggested Answer

Suggested Answer: C

Non-dihydropyridine calcium channel blockers -- which are diltiazem and verapamil -- are statistically more likely to cause constipation. Of these two, verapamil has a higher probability of causing this side effect.

by Sabra at Jan 05, 2023, 11:07 AM

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Toshia

1 days ago

This is a tricky one! I'm going to go with B) 20mg. If the oral to parenteral ratio is 7.5:1.5, then the oral dose is 5 times the parenteral dose. So, 0.5mg IV every 4 hours would be equivalent to 2.5mg orally every 4 hours, which adds up to 20mg per day.

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Peggie

12 days ago

I'm not sure, but I think the correct answer is A) 15mg based on the ratio provided.

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Jacob

13 days ago

I agree with Brandon, because the oral to parenteral ratio is 7.5:1.5.

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Stevie

16 days ago

I think the answer is C) 10mg. Based on the provided information, the oral to parenteral ratio is 7.5:1.5, so the equivalent oral dose would be 7.5 times the intravenous dose of 0.5mg, which is 3.75mg. Multiplying that by the daily dosing frequency of 6 (every 4 hours), the total daily oral dose would be 10mg.

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Brandon

24 days ago

I think the answer is A) 15mg.

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