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NABP NAPLEX Exam - Topic 7 Question 26 Discussion

After talking to the physician you find out her labs. Her labs reveled albumin level of 2.1gm/dL, calcium of 7.8mg/dL, glucose 120mg/dL , sodium 138 mmol/L, phenytoin level of 17.8.Based on the given data which of the following best interprets phenytoin concentration?
B) Phenytoin level is too high
A) Phenytoin level is with normal limits
C) Phenytoin level is too low
D) Phenytoin level cannot be determined
E) Phenytoin level need to be repeated

NABP NAPLEX Exam - Topic 7 Question 26 Discussion

Actual exam question for NABP's NAPLEX exam
Question #: 26
Topic #: 7
[All NAPLEX Questions]

After talking to the physician you find out her labs. Her labs reveled albumin level of 2.1gm/dL, calcium of 7.8mg/dL, glucose 120mg/dL , sodium 138 mmol/L, phenytoin level of 17.8.

Based on the given data which of the following best interprets phenytoin concentration?

Show Suggested Answer Hide Answer
Suggested Answer: B

Corrected phenytoin (mg/L) = Observed phenytoin (mg/L) / (0.2 x albumin [g/dL]) + 0.1 = 17.8 / (0.2 x 2.1) +

0.1 = 17.8 / 0.42 + 0.1 = 42.48mg/L phenytoin level is high. Normal therapeutic range is: 10-20mg/dL


by Bobbye at May 09, 2022, 01:50 PM

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Annamae
8 months ago
I agree, better to repeat the test just to be safe.
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Elsa
9 months ago
I thought it was supposed to be lower than that, not sure.
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Cecil
9 months ago
Wait, isn't the therapeutic range for phenytoin 10-20?
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Quentin
9 months ago
Definitely too high, I've seen this before.
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Polly
9 months ago
Phenytoin level is 17.8, which is high.
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Adelle
9 months ago
This question is similar to one we practiced where we had to consider lab values affecting drug levels. I think I might lean towards it being too high.
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Art
9 months ago
I’m not entirely sure, but I think low albumin levels can affect phenytoin levels, making it seem higher than it actually is.
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Stephen
9 months ago
I remember that normal phenytoin levels are usually between 10-20 mcg/mL, so 17.8 seems like it could be within normal limits.
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Aleta
9 months ago
I’m confused about whether we need to repeat the level or not. I feel like I’ve seen questions where they suggest repeating if there are abnormal labs.
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Cristen
9 months ago
Okay, let's see here. I'm pretty confident that A and C are the right answers - importing a panel configuration file and using the UI Extensions Editor. I'm not sure about the other options, but those two seem like the most straightforward ways to add a custom panel.
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Kristin
9 months ago
Okay, let me see here. The main objective is to track the movement of the money, right? That makes the most sense to me based on what I know about financial investigations. I'll go with option D.
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