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NABP NAPLEX Exam - Topic 6 Question 60 Discussion

Which of these cardiovascular drug classes is most associated with tachyphylaxis?
C) Direct renin inhibitors
A) ACE inhibitors
B) Angiotensin-receptor blockers
D) Calcium channel blockers
E) Nitrates

NABP NAPLEX Exam - Topic 6 Question 60 Discussion

Actual exam question for NABP's NAPLEX exam
Question #: 60
Topic #: 6
[All NAPLEX Questions]

Which of these cardiovascular drug classes is most associated with tachyphylaxis?

Show Suggested Answer Hide Answer
Suggested Answer: C

Non-dihydropyridine calcium channel blockers -- which are diltiazem and verapamil -- are statistically more likely to cause constipation. Of these two, verapamil has a higher probability of causing this side effect.


by Eun at Feb 25, 2023, 11:08 PM

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Sage
8 months ago
Nitrates are definitely the most associated with tachyphylaxis.
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Dorthy
8 months ago
ACE inhibitors can also show some tolerance, right?
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Kizzy
9 months ago
Wait, are we sure it's just nitrates?
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Delpha
9 months ago
Totally agree, nitrates can lose effectiveness quickly.
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Reta
9 months ago
Nitrates are the ones known for tachyphylaxis!
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Maddie
9 months ago
I feel like calcium channel blockers might have some relevance here too, but I can't recall the details.
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Kirk
9 months ago
I’m a bit confused; I thought ACE inhibitors could also cause some form of tolerance, but maybe not tachyphylaxis specifically?
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Tonette
9 months ago
I remember practicing a question about drug tolerance, and nitrates were definitely mentioned there.
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Leana
9 months ago
I think nitrates are the ones most associated with tachyphylaxis, but I’m not completely sure.
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Britt
9 months ago
Wait, I'm a little confused. Is the question asking about the purpose of the "Equipment" category, or is it asking us to identify the specific equipment-related causes of defects? I want to make sure I understand the question before I select an answer.
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Angelica
10 months ago
This is a classic contract law question. Offer, acceptance, and competent parties - that's the answer. I'm confident I've got this one nailed down.
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Quentin
1 year ago
Hey, at least we know the answer isn't the ACE inhibitors. Those guys are about as steady as a rock!
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Matilda
1 year ago
Angiotensin-receptor blockers, no doubt. They're the drama queens of the cardiovascular drug world.
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Micaela
1 year ago
I'm going with the calcium channel blockers on this one. They're about as reliable as a cheap watch.
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Daryl
1 year ago
I've heard that ACE inhibitors can also lead to tachyphylaxis over time.
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Nada
1 year ago
I think nitrates might also be associated with tachyphylaxis.
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Raul
1 year ago
I agree, calcium channel blockers can be unpredictable.
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Antonio
1 year ago
Direct renin inhibitors, for sure. Tachyphylaxis is their middle name!
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Niesha
1 year ago
I agree, direct renin inhibitors are the most associated with tachyphylaxis.
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Sommer
1 year ago
Direct renin inhibitors, definitely. They are known for causing tachyphylaxis.
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Tish
1 year ago
Hmm, I think it's gotta be the nitrates. Those babies can really lose their punch over time.
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Halina
1 year ago
I agree with Shelba, Calcium channel blockers can lead to tachyphylaxis due to their mechanism of action.
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Shelba
1 year ago
I disagree, I believe it's D) Calcium channel blockers because of their rapid tolerance development.
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Tomas
1 year ago
I think the answer is A) ACE inhibitors.
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