NABP Exam NAPLEX Topic 6 Question 25 Discussion

Actual exam question for NABP's North American Pharmacist Licensure Examination exam

Question #: 25
Topic #: 6

[All North American Pharmacist Licensure Examination Questions]

After talking to the patient you find out LT has been incompliant with her three times a day Valproic acid, level came back at 35 mmol/L.

What is the most appropriate course of action?

ANotify the physician to decrease the dose of Valproic acid.

BNotify the physician to increse the dose of Valproic acid.

CAlbumin needs to be obtained to calculate corrected Valproic acid level

DValproic acid level is within normal limit, no adjustment is needed.

Show Suggested Answer

Suggested Answer: D

The delayed-release action of divalproex allows for less frequent dosing than valproic acid in some patients. Divalproex sodium contains sodium valproate and valproic acid in a 1:1 molar stable co-ordination compound. Valproic acid, sodium valproate, and divalproex share the same pharmacology; however, there are pharmacokinetic differences among products.

by Penney at May 07, 2022, 01:52 PM

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