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NABP NAPLEX Exam - Topic 5 Question 119 Discussion

Posted by Therese on May 04, 2026 at 03:54 PM

Which of the following would be most appropriate to treat stenotrophomonas maltophilia?

Suggested Answer: D

Primary treatment for stenotrophomonas maltophilia is SMX-TMP. Meropenem, ciprofloxacin, and vancomycin have no coverage.


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24 comments · newest first
LA
Lashawna 2 days ago
Vancomycin won't work here, it's not the right spectrum.
ME
Merlyn 7 days ago
Right, D is the go-to option.
FR
Frank 12 days ago
Meropenem seems strong, but not for this bug.
MA
Malinda 17 days ago
D has solid evidence for treating stenotrophomonas.
LE
Leota 22 days ago
I was leaning towards C, but I see the point about D.
NO
Noe 28 days ago
Agreed, sulfamethoxazole/trimethoprim is effective against it.
ZA
Zana 1 month ago
I think D is the best choice.
CH
Chauncey 1 month ago
Definitely sticking with D for this one!
JA
Jame 1 month ago
Cefepime isn't recommended either.
LA
Laticia 2 months ago
Vancomycin won't help with this bacteria.
FL
Floyd 2 months ago
Ciprofloxacin could work, but not the first line.
SH
Sheron 2 months ago
Meropenem seems too broad for this.
RE
Reita 2 months ago
I read that it's the preferred treatment.
MA
Maia 2 months ago
Yeah, sulfamethoxazole/trimethoprim is effective.
AR
Aretha 2 months ago
I think D is the best choice.
GL
Glynda 3 months ago
100% agree, sulfamethoxazole/trimethoprim is the best choice!
AU
Audrie 3 months ago
Wait, is ciprofloxacin really an option? I’m not so sure.
CO
Cora 3 months ago
Definitely not vancomycin, that’s for sure!
LE
Lenny 3 months ago
I thought meropenem was effective too?
NO
Noah 3 months ago
Sulfamethoxazole/trimethoprim is the go-to for S. maltophilia.
JE
Jerry 4 months ago
I recall that ciprofloxacin can be used for some resistant infections, but I’m leaning towards sulfamethoxazole/trimethoprim based on what we practiced.
MA
Margurite 5 months ago
I’m a bit confused about vancomycin. I know it’s for Gram-positive bacteria, but does it have any effect on Stenotrophomonas?
JE
Jerlene 5 months ago
I feel like sulfamethoxazole/trimethoprim was mentioned in a practice question about this organism. It might be the right choice.
AM
Amie 5 months ago
I think I remember that Stenotrophomonas maltophilia is often resistant to many antibiotics, but I’m not sure if meropenem is effective.
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