NABP NAPLEX Exam - Topic 4 Question 61 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 61
Topic #: 4

[All NAPLEX Questions]

A 27-year-old female with ovarian cancer is undergoing chemotherapy. She develops subsequent renal failure.

Which of the following drugs is most likely responsible for this?

ACyclophosphamide

BBleomycin

CCisplatin

DVinblastine

EVincristine

Show Suggested Answer

Suggested Answer: A

Benign prostatic hyperplasia (BPH) is an example of postrenal acute kidney injury (AKI). Postrenal AKI, as the name suggests, involves an effect 'post' or 'beyond' the kidney, to problems that emerge downstream from the kidney. BPH is one such example of that. Other examples include kidney stones, bladder stones and bladder cancer.

by Charlene at Mar 23, 2023, 11:12 PM

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Alyce

8 months ago

Really? I’m surprised it’s not Bleomycin.

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Lynelle

8 months ago

Nope, definitely Cisplatin here.

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Adela

9 months ago

Wait, I thought it was just Cyclophosphamide that did that?

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Paulene

9 months ago

Totally agree, it's a common side effect.

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Van

9 months ago

Cisplatin is known for causing renal issues.

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Vivan

9 months ago

I'm really unsure about this one. I remember bleomycin being more about lung issues, but I can't recall the others clearly.

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Truman

9 months ago

I practiced a question similar to this, and I think it was about cisplatin being linked to renal failure. I hope that's right!

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Germaine

9 months ago

I think cyclophosphamide can affect the kidneys too, but I feel like cisplatin is more notorious for that.

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Thomasena

9 months ago

I remember reading that cisplatin can cause renal toxicity, but I'm not entirely sure if it's the most common one.

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Beckie

9 months ago

Okay, I remember learning about this in class. I think the KStream-GlobalKTable join is the one that doesn't require the same number of partitions.

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Chery

9 months ago

Okay, I think I've got this. The key is to create the contract in the right tenant and set the scope appropriately to prevent inter-tenant communication.

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Cherilyn

10 months ago

Okay, I remember learning about these types of plans in class. I think the key is to focus on the immediate recovery of operations after a disaster.

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Kiley

10 months ago

This seems like a straightforward question. I'll go with PolarDB MySQL since it's the closest to the database I'm currently using.

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Lelia

1 year ago

Wow, Cisplatin is really putting the 'fail' in 'renal failure'! Gotta be careful with that one.

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Dustin

1 year ago

D: Hopefully they can manage the renal failure and continue with the treatment.

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Dana

1 year ago

C: Definitely important to monitor kidney function closely during treatment.

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Wai

1 year ago

B: I heard it's a common side effect of chemotherapy drugs.

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Matt

1 year ago

A: Yeah, Cisplatin can be pretty harsh on the kidneys.

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Isabelle

1 year ago

Hmm, Cisplatin sounds like the culprit. Kidneys and chemo, not a good combo. Maybe we should start a support group for overworked oncology kidneys.

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Lezlie

1 year ago

We should definitely raise awareness about the potential side effects of chemotherapy drugs.

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Marg

1 year ago

Yeah, it's a tough situation for the kidneys to handle.

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Ariel

1 year ago

Cisplatin is definitely known for causing renal failure.

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Grover

1 year ago

Cisplatin, no doubt. It's like a double-edged sword - kills the cancer but can also take down the kidneys. Tricky stuff!

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Hubert

1 year ago

E) Vincristine

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Lon

1 year ago

D) Vinblastine

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Caprice

1 year ago

C) Cisplatin

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Tijuana

1 year ago

B) Bleomycin

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Octavio

1 year ago

A) Cyclophosphamide

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Adelle

1 year ago

My money's on Cisplatin too. Gotta watch out for those kidneys when using the heavy hitters.

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Laquita

1 year ago

Always important to monitor kidney function during chemotherapy.

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Sol

1 year ago

Yep, gotta be careful with those nephrotoxic drugs during chemo.

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Novella

1 year ago

Agreed, Cisplatin is a nephrotoxic drug.

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Pete

1 year ago

Definitely Cisplatin. It's known for causing renal failure.

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Audra

1 year ago

E) Vincristine

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Adela

1 year ago

D) Vinblastine

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Asha

1 year ago

C) Cisplatin

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Josephine

1 year ago

B) Bleomycin

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Meaghan

1 year ago

A) Cyclophosphamide

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Sarina

1 year ago

Yep, Cisplatin is a common culprit for renal failure in cancer patients.

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Luisa

1 year ago

Agreed, Cisplatin is notorious for its nephrotoxicity.

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Glendora

1 year ago

Definitely Cisplatin. It's known to cause renal failure.

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Marnie

1 year ago

E) Vincristine

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Brynn

1 year ago

D) Vinblastine

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Kati

1 year ago

C) Cisplatin

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Terrilyn

1 year ago

B) Bleomycin

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Jarvis

1 year ago

A) Cyclophosphamide

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Marsha

1 year ago

I'm not sure, but I think it could be A) Cyclophosphamide as well.

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Tayna

1 year ago

I agree with Nobuko. Cisplatin is known to cause renal failure.

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Alberto

1 year ago

Cisplatin is the obvious choice here. Renal toxicity is a well-known side effect of this chemotherapy drug.

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Hubert

1 year ago

Yeah, I agree. Cisplatin is notorious for its nephrotoxicity.

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Angelica

1 year ago

Cisplatin is definitely the culprit here. It's known for causing renal failure.

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Nobuko

1 year ago

I think the answer is C) Cisplatin.

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