NABP NAPLEX Exam - Topic 4 Question 45 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 45
Topic #: 4

A patient who weighs 80kg is ordered Esmolol at 50mcg/kg/min. Esmolol comes in 2500mg/250 ml NS premixed bags. What is the infusion rate in mls/hr?

A20mls/hr

B6mls/hr

C8mls/hr

D24mls/hr

E32mls/hr

Show Suggested Answer

Suggested Answer: D

50 mcg/kg/min 80 kg = 4 mg/min 60 min/hr = 240 mg/hr 2500 mg / 250 mL = 10 mg/mL 240 mg/hr / 10 mg/ mL = 24 mL/hr Esmolol Infusion

by Paris at May 05, 2022, 09:24 AM

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Mabel

7 months ago

Just double-checking, but isn't Esmolol super short-acting?

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Kiley

7 months ago

I disagree, I got 24mls/hr after my calculations.

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Barbra

7 months ago

Wait, how do you even calculate that? Seems tricky!

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Herschel

7 months ago

I think the answer is 32mls/hr, right?

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Lizette

8 months ago

The dose is 50mcg/kg/min for 80kg, so that's 4000mcg/min.

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Pearly

8 months ago

I feel like the answer is around 20mls/hr, but I can't recall how I got there. I need to double-check my calculations.

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Keena

8 months ago

I’m a bit confused about the conversion from mcg to mg. Was it 1000 mcg in a mg? I hope I remember that right.

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Krissy

8 months ago

I think we need to convert the mcg/kg/min to mg/min first, then figure out the total volume. It feels similar to that practice question we did last week.

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Jesusita

8 months ago

I remember we calculated infusion rates in pharmacology, but I'm not sure about the exact steps for this one.

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Carey

8 months ago

Hmm, this seems like a tricky one. I'll need to carefully consider the implications of the iterative life-cycle model and the available requirements information.

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Whitney

8 months ago

This seems like a tricky question. I'll need to think through the different Knowledge Module options carefully.

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