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NABP NAPLEX Exam - Topic 4 Question 45 Discussion

A patient who weighs 80kg is ordered Esmolol at 50mcg/kg/min. Esmolol comes in 2500mg/250 ml NS premixed bags. What is the infusion rate in mls/hr?
D) 24mls/hr
A) 20mls/hr
B) 6mls/hr
C) 8mls/hr
E) 32mls/hr

NABP NAPLEX Exam - Topic 4 Question 45 Discussion

Actual exam question for NABP's NAPLEX exam
Question #: 45
Topic #: 4
[All NAPLEX Questions]

A patient who weighs 80kg is ordered Esmolol at 50mcg/kg/min. Esmolol comes in 2500mg/250 ml NS premixed bags. What is the infusion rate in mls/hr?

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Suggested Answer: D

50 mcg/kg/min 80 kg = 4 mg/min 60 min/hr = 240 mg/hr 2500 mg / 250 mL = 10 mg/mL 240 mg/hr / 10 mg/ mL = 24 mL/hr Esmolol Infusion


by Paris at May 05, 2022, 09:24 AM

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Mabel
8 months ago
Just double-checking, but isn't Esmolol super short-acting?
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Kiley
9 months ago
I disagree, I got 24mls/hr after my calculations.
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Barbra
9 months ago
Wait, how do you even calculate that? Seems tricky!
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Herschel
9 months ago
I think the answer is 32mls/hr, right?
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Lizette
9 months ago
The dose is 50mcg/kg/min for 80kg, so that's 4000mcg/min.
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Pearly
9 months ago
I feel like the answer is around 20mls/hr, but I can't recall how I got there. I need to double-check my calculations.
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Keena
9 months ago
I’m a bit confused about the conversion from mcg to mg. Was it 1000 mcg in a mg? I hope I remember that right.
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Krissy
9 months ago
I think we need to convert the mcg/kg/min to mg/min first, then figure out the total volume. It feels similar to that practice question we did last week.
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Jesusita
9 months ago
I remember we calculated infusion rates in pharmacology, but I'm not sure about the exact steps for this one.
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Carey
9 months ago
Hmm, this seems like a tricky one. I'll need to carefully consider the implications of the iterative life-cycle model and the available requirements information.
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Whitney
10 months ago
This seems like a tricky question. I'll need to think through the different Knowledge Module options carefully.
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