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NABP NAPLEX Exam - Topic 4 Question 108 Discussion

Posted by Sue on Jul 08, 2025 at 04:09 AM

Which of the following Anti-epileptic medication can cause pancreatitis?

Suggested Answer: C

Cases of life-threatening pancreatitis have been reported in both pediatric and adult patients receiving valproic acid or its analogs. Patients should be warned that abdominal pain, nausea, vomiting, and/or anorexia can be symptoms of pancreatitis that require prompt medical evaluation. If pancreatitis is diagnosed, valproate should be discontinued.


http://www.clinicalpharmacology-ip.com/Forms/Monograph/monograph.aspx?cpnum=637&sec=moncontr&t=0

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14 comments · newest first
CA
Carey 10 months ago
Wait, are you sure about that? I thought it was rare.
TA
Tamekia 10 months ago
Yeah, I've read that too!
DE
Detra 10 months ago
I heard Valproic acid can cause pancreatitis.
JI
Jina 10 months ago
Carbamazepine is also a suspect, right?
TY
Ty 10 months ago
Gabapentin? No way, I didn't know that!
MA
Maile 11 months ago
I’m really unsure about this one. Gabapentin and levetiracetam don’t seem like they would cause pancreatitis, but I could be wrong.
ER
Ernestine 11 months ago
I practiced a question similar to this, and I believe valproic acid was the answer there too.
PE
Peggie 11 months ago
I remember reading something about carbamazepine, but I don't think it's linked to pancreatitis like valproic acid is.
SO
Soledad 11 months ago
I think valproic acid is the one that can cause pancreatitis, but I'm not completely sure.
CA
Cathrine 12 months ago
Ah, I'm drawing a blank on the specifics of which anti-epileptic meds can cause pancreatitis. I'll just have to make an educated guess and go with B.
RO
Rory 12 months ago
I remember learning that valproic acid can cause pancreatitis, so I'm going to go with C on this one.
MA
Margurite 12 months ago
Okay, let me think this through. Carbamazepine, valproic acid, and phenobarbital are all common anti-epileptic drugs, so one of those is likely the answer. I'll eliminate the ones I'm less sure about and go with C.
KE
Kent 1 year ago
Hmm, I'm not totally sure about this one. I know some anti-epileptic meds can cause pancreatitis, but I'd have to double-check my notes to be confident in the answer.
CL
Clorinda 1 year ago
I'm pretty sure I've seen pancreatitis listed as a potential side effect of carbamazepine, so I'll go with A.
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