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NABP NAPLEX Exam - Topic 4 Question 108 Discussion

Which of the following Anti-epileptic medication can cause pancreatitis?
C) Valproic acid
A) Carbamazepine
B) Gabapentin
D) Levetiracetam
E) Phenobarbital

NABP NAPLEX Exam - Topic 4 Question 108 Discussion

Actual exam question for NABP's NAPLEX exam
Question #: 108
Topic #: 4
[All NAPLEX Questions]

Which of the following Anti-epileptic medication can cause pancreatitis?

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Suggested Answer: C

Cases of life-threatening pancreatitis have been reported in both pediatric and adult patients receiving valproic acid or its analogs. Patients should be warned that abdominal pain, nausea, vomiting, and/or anorexia can be symptoms of pancreatitis that require prompt medical evaluation. If pancreatitis is diagnosed, valproate should be discontinued.


http://www.clinicalpharmacology-ip.com/Forms/Monograph/monograph.aspx?cpnum=637&sec=moncontr&t=0

by Sue at Jul 08, 2025, 04:09 AM

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Carey
7 months ago
Wait, are you sure about that? I thought it was rare.
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Tamekia
7 months ago
Yeah, I've read that too!
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Detra
7 months ago
I heard Valproic acid can cause pancreatitis.
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Jina
7 months ago
Carbamazepine is also a suspect, right?
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Ty
7 months ago
Gabapentin? No way, I didn't know that!
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Maile
8 months ago
I’m really unsure about this one. Gabapentin and levetiracetam don’t seem like they would cause pancreatitis, but I could be wrong.
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Ernestine
8 months ago
I practiced a question similar to this, and I believe valproic acid was the answer there too.
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Peggie
8 months ago
I remember reading something about carbamazepine, but I don't think it's linked to pancreatitis like valproic acid is.
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Soledad
8 months ago
I think valproic acid is the one that can cause pancreatitis, but I'm not completely sure.
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Cathrine
9 months ago
Ah, I'm drawing a blank on the specifics of which anti-epileptic meds can cause pancreatitis. I'll just have to make an educated guess and go with B.
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Rory
9 months ago
I remember learning that valproic acid can cause pancreatitis, so I'm going to go with C on this one.
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Margurite
9 months ago
Okay, let me think this through. Carbamazepine, valproic acid, and phenobarbital are all common anti-epileptic drugs, so one of those is likely the answer. I'll eliminate the ones I'm less sure about and go with C.
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Kent
9 months ago
Hmm, I'm not totally sure about this one. I know some anti-epileptic meds can cause pancreatitis, but I'd have to double-check my notes to be confident in the answer.
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Clorinda
9 months ago
I'm pretty sure I've seen pancreatitis listed as a potential side effect of carbamazepine, so I'll go with A.
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