NABP NAPLEX Exam - Topic 4 Question 108 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 108
Topic #: 4

[All NAPLEX Questions]

Which of the following Anti-epileptic medication can cause pancreatitis?

ACarbamazepine

BGabapentin

CValproic acid

DLevetiracetam

EPhenobarbital

Show Suggested Answer

Suggested Answer: C

Cases of life-threatening pancreatitis have been reported in both pediatric and adult patients receiving valproic acid or its analogs. Patients should be warned that abdominal pain, nausea, vomiting, and/or anorexia can be symptoms of pancreatitis that require prompt medical evaluation. If pancreatitis is diagnosed, valproate should be discontinued.

http://www.clinicalpharmacology-ip.com/Forms/Monograph/monograph.aspx?cpnum=637&sec=moncontr&t=0

by Sue at Jul 08, 2025, 04:09 AM

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Carey

2 months ago

Wait, are you sure about that? I thought it was rare.

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Tamekia

2 months ago

Yeah, I've read that too!

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Detra

2 months ago

I heard Valproic acid can cause pancreatitis.

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Jina

3 months ago

Carbamazepine is also a suspect, right?

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Ty

3 months ago

Gabapentin? No way, I didn't know that!

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Maile

3 months ago

I’m really unsure about this one. Gabapentin and levetiracetam don’t seem like they would cause pancreatitis, but I could be wrong.

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Ernestine

3 months ago

I practiced a question similar to this, and I believe valproic acid was the answer there too.

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Peggie

4 months ago

I remember reading something about carbamazepine, but I don't think it's linked to pancreatitis like valproic acid is.

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Soledad

4 months ago

I think valproic acid is the one that can cause pancreatitis, but I'm not completely sure.

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Cathrine

4 months ago

Ah, I'm drawing a blank on the specifics of which anti-epileptic meds can cause pancreatitis. I'll just have to make an educated guess and go with B.

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Rory

4 months ago

I remember learning that valproic acid can cause pancreatitis, so I'm going to go with C on this one.

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Margurite

4 months ago

Okay, let me think this through. Carbamazepine, valproic acid, and phenobarbital are all common anti-epileptic drugs, so one of those is likely the answer. I'll eliminate the ones I'm less sure about and go with C.

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Kent

5 months ago

Hmm, I'm not totally sure about this one. I know some anti-epileptic meds can cause pancreatitis, but I'd have to double-check my notes to be confident in the answer.

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Clorinda

5 months ago

I'm pretty sure I've seen pancreatitis listed as a potential side effect of carbamazepine, so I'll go with A.

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