NABP NAPLEX Exam - Topic 10 Question 49 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 49
Topic #: 10

[All NAPLEX Questions]

Which H2-receptor blocker may cause gynecomastia in men due to its antiandrogenic effects?

ARanitidine

BNizatidine

CCimetidine

DFamotidine

Show Suggested Answer

Suggested Answer: C

Cimetidine has multiple drug interactions due to its inhibitory effects on CYP1A2, 2C9, 2D6, and 3A4. Inhibition of these enzymes can cause an increase in the serum concentrations of drugs metabolized by these enzymes, leading to toxicity.

by Merlyn at Jul 26, 2022, 04:03 PM

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Vivan

4 months ago

Ranitidine and famotidine don’t have that issue.

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Clare

4 months ago

Cimetidine has antiandrogenic effects, so it makes sense.

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Yaeko

4 months ago

Wait, really? I thought all H2 blockers were safe.

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Scarlet

4 months ago

Totally agree, it's known for that side effect.

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Daron

4 months ago

Cimetidine is the one that can cause gynecomastia.

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Mel

5 months ago

I remember discussing this in class, and Cimetidine definitely stood out for its side effects. I hope I’m right!

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Amber

5 months ago

I’m a bit confused. I thought Ranitidine could also cause some hormonal issues, but maybe that’s just a mix-up from practice questions.

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Jacqueline

5 months ago

Yeah, I also recall Cimetidine being the one linked to gynecomastia. I think it has antiandrogenic properties.

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Cristen

5 months ago

I think it might be Cimetidine, but I’m not completely sure. I remember it has some weird side effects.

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Devon

5 months ago

Okay, let me walk through this step-by-step. I think the key is understanding how script variables work in the designer.

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Brynn

5 months ago

This looks like a straightforward Azure Virtual Desktop question. I think the key is to focus on the requirements of high IOPS and low latency for the FSLogix profile containers.

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Ozell

5 months ago

Okay, I've got this. The Stored Procedure transformation can have Input, Output, and Return ports. The Variable port type doesn't seem to apply here, so I'll skip that one.

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Shaun

5 months ago

I'm a bit confused on the best practice here. I know tempdb is important for performance, but I'm not sure how to determine the optimal number of data files.

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