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Which H2-receptor blocker may cause gynecomastia in men due to its antiandrogenic effects?
Suggested Answer: C
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Cimetidine has multiple drug interactions due to its inhibitory effects on CYP1A2, 2C9, 2D6, and 3A4. Inhibition of these enzymes can cause an increase in the serum concentrations of drugs metabolized by these enzymes, leading to toxicity.
13 comments · newest first
VI
Vivan
11 months ago
Ranitidine and famotidine don’t have that issue.
CL
Clare
11 months ago
Cimetidine has antiandrogenic effects, so it makes sense.
YA
Yaeko
12 months ago
Wait, really? I thought all H2 blockers were safe.
SC
Scarlet
12 months ago
Totally agree, it's known for that side effect.
DA
Daron
12 months ago
Cimetidine is the one that can cause gynecomastia.
ME
Mel
1 year ago
I remember discussing this in class, and Cimetidine definitely stood out for its side effects. I hope I’m right!
AM
Amber
1 year ago
I’m a bit confused. I thought Ranitidine could also cause some hormonal issues, but maybe that’s just a mix-up from practice questions.
JA
Jacqueline
1 year ago
Yeah, I also recall Cimetidine being the one linked to gynecomastia. I think it has antiandrogenic properties.
CR
Cristen
1 year ago
I think it might be Cimetidine, but I’m not completely sure. I remember it has some weird side effects.
DE
Devon
1 year ago
Okay, let me walk through this step-by-step. I think the key is understanding how script variables work in the designer.
BR
Brynn
1 year ago
This looks like a straightforward Azure Virtual Desktop question. I think the key is to focus on the requirements of high IOPS and low latency for the FSLogix profile containers.
OZ
Ozell
1 year ago
Okay, I've got this. The Stored Procedure transformation can have Input, Output, and Return ports. The Variable port type doesn't seem to apply here, so I'll skip that one.
SH
Shaun
1 year ago
I'm a bit confused on the best practice here. I know tempdb is important for performance, but I'm not sure how to determine the optimal number of data files.