Deal of The Day! Hurry Up, Grab the Special Discount - Save 25% - Ends In 00:00:00 Coupon code: SAVE25
Free Preparation Discussions
MENU
NABP Exam NAPLEX Topic 10 Question 18 Discussion
Actual exam question for
NABP's
North American Pharmacist Licensure Examination exam
Question #: 18
Topic #: 10
[All North American Pharmacist Licensure Examination Questions]
Topic #: 10
Concomitant use of warfarin and omeprazole is associated with increased INR and prothrombin time(PT). What enzyme dose the omeprazole inhibits that is metabolized by warfarin?
Suggested Answer:
C
Omeprazole is CYP2C19 inhibitor which can prolong the elimination of warfarin, particularly R-warfarin. R- warfarin is partially metabolized by CYP2C19. The combined use of omeprazole and warfarin has been associated with reports of increased INR and prothrombin time (PT).
Currently there are no comments in this discussion, be the first to comment!