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NABP NAPLEX Exam - Topic 1 Question 24 Discussion

Actual exam question for NABP's NAPLEX exam
Question #: 24
Topic #: 1
[All NAPLEX Questions]

Which of the following is recommended to be monitored in patients on Divalproex Sodium?

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Suggested Answer: C

A, B, C. Hepatotoxicity, including hepatic failure, has been fatal and may more commonly occur in the first 6 months of treatment. Valproic acid and its analogs are contraindicated in patients with known urea cycle disorders. Patients with urea cycle disorders have a genetic enzyme defect leading to an impaired ability to produce urea. Hyperammonemic encephalopathy has been reported following initiation of valproate therapy. Because of, inhibition of the secondary phase of platelet aggregation, and abnormal coagulation parameters complete blood counts and coagulation tests are recommended before initiating valproic acid therapy and at periodic intervals.


by Beckie at May 09, 2022, 06:14 AM

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Dianne
4 months ago
Wait, do we really need to check pulmonary function?
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Elina
4 months ago
Agreed on LFT's, but surprised about ammonia too.
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Peggy
4 months ago
I thought CBC was the main one to watch?
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Dong
4 months ago
Serum ammonia is also important!
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Kimberlie
5 months ago
Definitely need to monitor LFT's with Divalproex.
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Maynard
5 months ago
I’m a bit confused about the pulmonary function monitoring; I don't recall that being a standard recommendation for Divalproex.
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Carman
5 months ago
I practiced a question like this, and I feel like serum ammonia is also important to check, especially for signs of toxicity.
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Margot
5 months ago
I remember something about monitoring LFTs because Divalproex can affect liver function, right?
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Georgene
5 months ago
I think we need to monitor CBC for patients on Divalproex Sodium, but I'm not entirely sure if that's the most critical one.
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Dyan
5 months ago
This looks like a straightforward email design question. I think the key is to make it as easy as possible for customers to provide feedback, so an interactive email form that links to a confirmation page seems like the best approach.
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Eileen
5 months ago
This seems like a tricky one. I'll need to think it through carefully.
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Chauncey
5 months ago
This requires careful calculation. I'll look for an option that seems mathematically aligned with the scenario's requirements.
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Merissa
5 months ago
Hmm, I'm not totally sure about this one. Is it the product itself or the customer benefits? I'll have to think it through carefully.
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