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NABP NAPLEX Exam - Topic 1 Question 20 Discussion

Actual exam question for NABP's NAPLEX exam
Question #: 20
Topic #: 1
[All NAPLEX Questions]

What indication usually requires higher dose of proton pump inhibitor?

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Suggested Answer: E

The diagnosis of Zollinger-Ellison syndrome is suggested when plasma gastrin is > 1000 pg/ml and the basal acid output is > 15 mEq/h or when associated with a pH < 2. The treatment is focused on controlling gastric acid hypersecretion and localisation of the tumour and its metastases. Proton pump inhibitors are the most effective antisecretory drugs and can be administered at high dosages


by Earleen at May 07, 2022, 07:31 PM

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Alida
4 months ago
Stress ulcer prophylaxis can also need higher doses sometimes.
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Malcolm
4 months ago
Wait, really? I didn't know that about Zollinger-Ellison!
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Carol
4 months ago
I thought esophagitis required more too?
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Hyun
4 months ago
Totally agree, that's a big one.
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Virgilio
5 months ago
Zollinger-Ellison syndrome needs higher doses!
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Tasia
5 months ago
I feel like duodenal ulcers usually get standard doses, but I could be wrong about that.
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Willard
5 months ago
Esophagitis sounds familiar for needing a higher dose, but I might be mixing it up with something else.
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Gayla
5 months ago
I remember practicing a question about stress ulcer prophylaxis, but I can't recall if it needs a higher dose or not.
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Helaine
5 months ago
I think Zollinger-Ellison syndrome might require a higher dose, but I'm not entirely sure.
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Francis
5 months ago
Hmm, the elbow plot shows a clear bend around 3 or 4 clusters, so I'd say those are good options to consider.
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Adrianna
5 months ago
Okay, let me see. The question is asking about a valid query, so I'll need to check the syntax and make sure the aggregation makes sense.
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