NABP NAPLEX Exam - Topic 1 Question 101 Discussion

Actual exam question for NABP's NAPLEX exam

Question #: 101
Topic #: 1

[All NAPLEX Questions]

Mesna is typically administered alongside which of these chemotherapeutic agents?

ABusulfan

BPaclitaxel

CIfosfamide

DDoxorubicin

Show Suggested Answer

Suggested Answer: C

Mesna is administered to patients taking either ifosfamide or cyclophoshamide to conjugate toxic acrolein and therefore prevent hemorrhagic cystitis (bladder bleeding).

by Laura at Feb 12, 2025, 07:27 PM

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Yvette

4 months ago

Yeah, I've seen it used with Ifosfamide in practice.

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Melita

5 months ago

Nope, definitely Ifosfamide.

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Carlota

5 months ago

Wait, I thought it was for Busulfan?

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Cherry

5 months ago

Totally agree, it's a protective agent for that drug!

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Tamra

5 months ago

Mesna is usually given with Ifosfamide.

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Antione

5 months ago

I’m pretty confident it’s Ifosfamide. I remember Mesna is used to prevent bladder toxicity with that drug.

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Suzi

6 months ago

I’m torn between Ifosfamide and Busulfan. I feel like I’ve seen both in practice questions, but I can’t recall which one is correct.

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Avery

6 months ago

I remember practicing a question about Mesna and its use with chemotherapeutics. Ifosfamide definitely rings a bell.

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Nichelle

6 months ago

I think Mesna is used with Ifosfamide, but I’m not completely sure. It’s been a while since I reviewed that section.

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Viva

6 months ago

Ah, I'm drawing a blank on this one. I'll have to make an educated guess and go with B, paclitaxel.

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Christiane

6 months ago

Okay, I remember learning that mesna is a uroprotective agent used to prevent hemorrhagic cystitis, which can be a side effect of certain chemotherapies. I think the answer is C, ifosfamide.

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Stephaine

6 months ago

Hmm, I'm a bit unsure about this one. I'll have to think it through carefully before answering.

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Annmarie

6 months ago

I'm pretty sure mesna is used with ifosfamide, so I'll go with option C.

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Avery

1 year ago

Ah, the age-old question - Mesna and what chemo agent? I bet someone in the back is already yelling, 'It's Ifosfamide, you fools!'

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Lindsey

1 year ago

C'mon, everyone knows it's Ifosfamide! Mesna and Ifosfamide are like peanut butter and jelly, you can't have one without the other.

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Juliann

1 year ago

That's right, they work together to protect the bladder.

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Frederica

1 year ago

I agree, Mesna is always given with Ifosfamide.

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Lanie

1 year ago

Hmm, I'm pretty sure it's Ifosfamide. Although, I heard Doxorubicin can also cause some nasty bladder issues, so maybe that's it? Better double-check the notes.

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