Pulmonary artery end-diastolic pressure (PAEDP) can be estimated noninvasively by measuring the end-diastolic velocity of pulmonary regurgitation (pulmonary insufficiency) using continuous-wave Doppler. The pressure gradient between the pulmonary artery and right ventricle at end-diastole is calculated using the modified Bernoulli equation from this velocity.

Tricuspid insufficiency is used to estimate right ventricular systolic pressure. Tricuspid inflow and pulmonary inflow velocities provide information on diastolic function but not direct pressure gradients.

This method is well validated and included in ASE guidelines for pulmonary hypertension assessment and Doppler hemodynamics16:Textbook of Clinical Echocardiography, 6ep.300-30512:ASE Doppler Guidelinesp.110-115.