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NABP FPGEE Exam - Topic 7 Question 65 Discussion

Posted by Merilyn on Jul 08, 2023 at 01:42 PM

Mechanism of resistance of dicloxacillin is:

Suggested Answer: D

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37 comments · newest first
LI
Lindsey 11 months ago
I thought mutations in M protein were more common.
ER
Ernie 11 months ago
Antibodies from strep infection? That sounds off.
HO
Howard 11 months ago
Wait, are we sure it's not just decreased drug uptake?
RO
Robt 11 months ago
Definitely agree, PBPs are key here too.
SO
Sonia 12 months ago
It's all about the beta-lactamase!
RO
Rodolfo 12 months ago
I don't remember much about E, but antibodies from streptococcal infections seem unrelated to dicloxacillin resistance. I lean towards C or D.
SA
Sang 12 months ago
I recall a practice question about resistance mechanisms, and I think decreased drug uptake was mentioned, so maybe A is a possibility too?
QU
Quentin 1 year ago
I'm not entirely sure, but I feel like it could also be related to D, the penicillin binding proteins. We discussed that in class.
CL
Clarinda 1 year ago
I think the answer might be C, beta-lactamase, since I remember it being a common resistance mechanism for penicillins.
GE
Gerald 1 year ago
Ooh, this is an interesting one! I like the idea of using a custom object to store the questions and answers, and then leveraging LWC to display them dynamically. That could give us a lot of flexibility and control over the user experience.
JU
Juliana 1 year ago
Hmm, this looks like a tricky one. I'll need to think carefully about the diagnostic tools used with Backup Exec.
RE
Remedios 1 year ago
Okay, let me think this through. GV is expanding into a new product category (leather shoes) in a new market (country P), so I believe the correct answer is related diversification.
WI
William 1 year ago
I'm just going to go with C) Beta-lactamase and hope for the best. If this is wrong, I'll be dicloxappointed.
LA
Lashaun 1 year ago
E) Antibodies resulting from streptococcal infection? Really? That's just silly. Maybe the exam writers have a twisted sense of humor.
DO
Donette 1 year ago
↳ replying to Lashaun
D) Penicillin binding proteins (PBPs)
MA
Marti 1 year ago
↳ replying to Lashaun
C) Beta-lactamase
DE
Demetra 1 year ago
↳ replying to Lashaun
A) Decreased drug uptake by bacteria
GI
Gianna 1 year ago
This is a tricky one. I'm going to go with B) Mutations in M (matrix) protein. Sounds like something a sneaky bacteria would do.
ME
Melodie 1 year ago
Hmm, I'm not so sure. I was thinking it might be D) Penicillin binding proteins (PBPs). Isn't that how some bacteria become resistant?
CO
Cory 1 year ago
↳ replying to Melodie
E) Antibodies resulting from streptococcal infection
MI
Mirta 1 year ago
↳ replying to Melodie
C) Beta-lactamase
JO
Josefa 1 year ago
↳ replying to Melodie
A) Decreased drug uptake by bacteria
CH
Chaya 1 year ago
I think it's definitely C) Beta-lactamase. That's the classic mechanism for penicillin resistance.
GO
Golda 1 year ago
↳ replying to Chaya
I've heard that some bacteria can also develop mutations in M protein.
BE
Berry 1 year ago
↳ replying to Chaya
True, PBPs can also play a role in resistance.
JO
Jodi 1 year ago
↳ replying to Chaya
But I think it could also be D) Penicillin binding proteins (PBPs).
BL
Blair 1 year ago
↳ replying to Chaya
I agree, Beta-lactamase is a common mechanism for resistance.
SA
Salome 1 year ago
↳ replying to Chaya
It's interesting how bacteria can develop different mechanisms to resist antibiotics.
HO
Hollis 1 year ago
↳ replying to Chaya
True, PBPs can definitely contribute to resistance as well.
SA
Sabra 1 year ago
↳ replying to Chaya
I think it could also be D) Penicillin binding proteins (PBPs) playing a role.
RO
Roslyn 1 year ago
↳ replying to Chaya
I agree, Beta-lactamase is a common mechanism for resistance.
OL
Oliva 1 year ago
I believe it's Penicillin binding proteins (PBPs) that are responsible for resistance to dicloxacillin.
DA
Daryl 1 year ago
I agree with Wenona, Beta-lactamase can break down dicloxacillin.
WE
Wenona 2 years ago
I think the mechanism of resistance of dicloxacillin is Beta-lactamase.
RO
Royal 2 years ago
Hmm, that makes sense too. Beta-lactamase can definitely break down dicloxacillin.
LA
Lavonna 2 years ago
I disagree, I believe it is because of beta-lactamase production by bacteria.
RO
Royal 2 years ago
I think the mechanism of resistance of dicloxacillin is due to mutations in M protein.
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