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NABP Exam FPGEE Topic 6 Question 94 Discussion

Actual exam question for NABP's FPGEE exam
Question #: 94
Topic #: 6
[All FPGEE Questions]

In an adequately powered, randomized controlled trial conducted over 2 years, the desired clinical outcome (i.e. prevention of a serious cardiovascular event) with a new drug is achieved in 25% of the study sample. In the patients who receive a placebo, only 15% obtain the same clinical benefit. The relative risk reduction achieved with the new drug over the study period is:

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Suggested Answer: B

by Kiley at Sep 13, 2024, 06:31 PM

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Yuonne
7 days ago
I think the answer is D) 40%. The relative risk reduction is the difference in the event rate between the treatment and placebo groups, divided by the event rate in the placebo group. In this case, it's (25% - 15%) / 15% = 0.4 or 40%.
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Ellen
15 days ago
I'm not sure, but I think the answer might be D) 40% because the difference between 25% and 15% is 10%, which is 40% of 25%.
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Daren
18 days ago
I agree with Ruth, the relative risk reduction is 25% because the new drug achieved a 10% higher clinical outcome compared to the placebo.
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Ruth
19 days ago
I think the answer is C) 25%.
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