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NABP Exam FPGEE Topic 6 Question 94 Discussion

Actual exam question for NABP's FPGEE exam
Question #: 94
Topic #: 6
[All FPGEE Questions]

In an adequately powered, randomized controlled trial conducted over 2 years, the desired clinical outcome (i.e. prevention of a serious cardiovascular event) with a new drug is achieved in 25% of the study sample. In the patients who receive a placebo, only 15% obtain the same clinical benefit. The relative risk reduction achieved with the new drug over the study period is:

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Suggested Answer: B

by Kiley at Sep 13, 2024, 06:31 PM

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Tambra
1 months ago
Ugh, I knew this one would be tricky. At least I can eliminate the wrong answers and narrow it down. Relative risk reduction, not absolute risk - got it, thanks Yuonne!
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Ozell
2 days ago
B) 15%.
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Marg
4 days ago
A) 10%.
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Altha
2 months ago
I was going to say E) 50%, but now I see my mistake. Relative risk reduction is not the same as absolute risk reduction. Silly me, I should have paid more attention in class.
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Jamal
2 months ago
Definitely D) 40%. I'm glad I reviewed the relative risk reduction concept before the exam. It's a common question type in these kinds of trials.
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Pamella
16 days ago
D) 40%.
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Xenia
21 days ago
C) 25%.
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Skye
1 months ago
B) 15%.
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Deonna
1 months ago
A) 10%.
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Elvis
2 months ago
I was thinking the same, Yuonne. The relative risk reduction formula is straightforward, and the numbers provided make it a simple calculation.
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Denise
22 days ago
C) 25%
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Jaclyn
25 days ago
B) 15%
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Timothy
1 months ago
A) 10%
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Yuonne
2 months ago
I think the answer is D) 40%. The relative risk reduction is the difference in the event rate between the treatment and placebo groups, divided by the event rate in the placebo group. In this case, it's (25% - 15%) / 15% = 0.4 or 40%.
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Malcolm
26 days ago
I agree with the explanation, it is indeed D) 40%.
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Kizzy
1 months ago
That makes sense, the relative risk reduction is calculated by comparing the event rates between the treatment and placebo groups.
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Andrew
1 months ago
I'm pretty sure it's A) 10%.
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Omega
1 months ago
I agree, the answer is D) 40%.
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Thea
2 months ago
I think it's actually E) 50%.
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Melynda
2 months ago
I believe the answer is D) 40%.
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Ellen
3 months ago
I'm not sure, but I think the answer might be D) 40% because the difference between 25% and 15% is 10%, which is 40% of 25%.
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Daren
3 months ago
I agree with Ruth, the relative risk reduction is 25% because the new drug achieved a 10% higher clinical outcome compared to the placebo.
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Ruth
3 months ago
I think the answer is C) 25%.
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