NABP FPGEE Exam - Topic 6 Question 107 Discussion

Actual exam question for NABP's FPGEE exam

Question #: 107
Topic #: 6

Which of the following statements refers to foscavir?

APyrophosphate analog

BMetabolism in liver is by glucuronidization

CNot shown to reduce sudden death or prolong survival.

DInhibition of DNA gyrase results in: 1. Inhibition of bacterial replication 2. Inhibition of DNA repair 3. Inhibition of expression of certain operons

ENon-nucleoside reverse transcriptase inhibitor

Show Suggested Answer

Suggested Answer: A

by Dottie at Jul 07, 2025, 01:58 PM

Limited Time Offer

25%

Off

Get Premium FPGEE Questions as Interactive Web-Based Practice Test or PDF

Contribute your Thoughts:

Submit Cancel

Sabra

7 months ago

Metabolism by glucuronidization is correct, good point!

upvoted 0 times

...

Marvel

7 months ago

Wait, isn't it also used for CMV infections?

upvoted 0 times

...

Amalia

7 months ago

Foscavir is a pyrophosphate analog.

upvoted 0 times

...

Latia

7 months ago

Not sure about that sudden death claim, sounds off to me.

upvoted 0 times

...

Twila

7 months ago

Totally agree, it's definitely not a reverse transcriptase inhibitor.

upvoted 0 times

...

Leanora

8 months ago

The options about DNA gyrase seem off; I thought that was more related to antibiotics than foscavir.

upvoted 0 times

...

Clay

8 months ago

I feel like there was a practice question about foscavir not affecting survival rates, but I can't remember the details.

upvoted 0 times

...

Nida

8 months ago

I remember something about its mechanism, but I can't recall if it has anything to do with liver metabolism.

upvoted 0 times

...

Cassie

8 months ago

I think foscavir is a pyrophosphate analog, but I'm not entirely sure if that's the right term.

upvoted 0 times

...

Kendra

8 months ago

I'll start by eliminating the options that don't sound right, then focus on the remaining ones.

upvoted 0 times

...

Stephanie

9 months ago

Wait, what is foscavir again? I'm a little fuzzy on the details.

upvoted 0 times

...

Amina

9 months ago

Okay, let me think this through step-by-step. I've got this.

upvoted 0 times

...

Amie

9 months ago

Hmm, I'm not too sure about this one. I'll have to read through the options carefully.

upvoted 0 times

...

Gregoria

9 months ago

This question seems straightforward, I think I can handle it.

upvoted 0 times

...

Erin

11 months ago

Haha, E is definitely not the answer. Foscavir is an antiviral, not a reverse transcriptase inhibitor like the ones used for HIV.

upvoted 0 times

...

Raul

11 months ago

I think D is the best choice. Foscavir inhibits DNA gyrase, which impacts bacterial replication, DNA repair, and gene expression.

upvoted 0 times

Tien

10 months ago

B) Metabolism in liver is by glucuronidization

upvoted 0 times

...

Edwin

10 months ago

A) Pyrophosphate analog

upvoted 0 times

...

Karrie

11 months ago

C is the right answer. Foscavir is not shown to reduce sudden death or prolong survival, unlike some other antiviral drugs.

upvoted 0 times

Flo

10 months ago

upvoted 0 times

...

Jacinta

11 months ago

That makes sense, I'll go with E) Non-nucleoside reverse transcriptase inhibitor too.

upvoted 0 times

...

Arlyne

11 months ago

I heard that foscavir is used to treat cytomegalovirus infections, so maybe it is E) Non-nucleoside reverse transcriptase inhibitor.

upvoted 0 times

...

Lottie

11 months ago

I'm not sure, but I think it might be D) Inhibition of DNA gyrase.

upvoted 0 times

...

Barb

12 months ago

Option A seems correct. Foscavir is a pyrophosphate analog that inhibits viral DNA polymerase.

upvoted 0 times

Nidia

10 months ago

That's right! Foscavir works by inhibiting viral DNA polymerase as a pyrophosphate analog.

upvoted 0 times

...

Cristal

11 months ago

Yes, you are correct. Foscavir is indeed a pyrophosphate analog that inhibits viral DNA polymerase.

upvoted 0 times

...

Jacinta

12 months ago

I disagree, I believe it is E) Non-nucleoside reverse transcriptase inhibitor.

upvoted 0 times

...

Arlyne

1 year ago

I think the answer is A) Pyrophosphate analog.

upvoted 0 times

...