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NABP FPGEE Exam - Topic 5 Question 110 Discussion

Posted by Jamika on Aug 15, 2025 at 08:25 PM

What would be the preferred route of metabolism of succinyl choline?

Suggested Answer: C

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18 comments · newest first
BE
Bettina 9 months ago
Surprised to see N-oxidation mentioned at all!
CR
Cristal 10 months ago
I agree, A is the preferred route for succinyl choline.
CA
Casandra 10 months ago
I think it's mainly ester hydrolysis.
CO
Cory 10 months ago
Wait, are you sure about that? I thought N-oxidation played a role too.
VE
Verona 10 months ago
Definitely A, that’s the classic route!
VI
Vincent 11 months ago
I recall that succinyl choline is rapidly broken down, but I can't remember if it involves glucuronide conjugation or just ester hydrolysis.
LI
Linette 11 months ago
I’m a bit confused about N-oxidation. Is that really a common pathway for succinyl choline?
BR
Brande 11 months ago
I remember practicing a similar question where we discussed drug metabolism pathways. I feel like A is the most likely answer here.
KA
Kassandra 11 months ago
I think succinyl choline is primarily metabolized by ester hydrolysis, but I'm not completely sure.
HO
Hoa 12 months ago
Okay, let me think this through step-by-step. Succinyl choline is an ester, so ester hydrolysis makes sense as the preferred route. I'll go with that.
LA
Lashunda 12 months ago
I remember learning about the metabolism of succinyl choline in class. I think the preferred route is ester hydrolysis, but I'll re-read the question to confirm.
BR
Brittney 12 months ago
Ester hydrolysis is a common metabolic pathway for drugs, so that's my first guess. But I'll double-check the other options just to be sure.
BE
Bernardine 1 year ago
Hmm, I'm not too familiar with succinyl choline, so I'll have to think this through carefully.
AN
Anjelica 1 year ago
This looks like a question about the metabolism of a drug, so I'll need to think about the common metabolic pathways for drugs.
KA
Kattie 1 year ago
I agree with Leigha, succinyl choline is usually metabolized through ester hydrolysis.
LE
Leigha 1 year ago
I think the preferred route would be A) Ester hydrolysis.
EM
Emily 1 year ago
Hmm, I'd go with option A. Ester hydrolysis is the way to go for succinylcholine. Gotta love those classic pharmacokinetics!
AS
Ashley 1 year ago
Ester hydrolysis, no doubt! That's the preferred route for succinylcholine metabolism. Easy peasy!
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