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NABP FPGEE Exam - Topic 4 Question 92 Discussion

Posted by Marta on Sep 13, 2024 at 02:36 AM

In some parenteral formulations, sodium metabisulphite is included as:

Suggested Answer: B

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40 comments · newest first
NA
Nan 10 months ago
Just a heads up, it’s definitely not an emulsifier.
KA
Kandis 11 months ago
I thought it was a solubilizer, but I guess I was wrong!
IR
Irene 11 months ago
Wait, are we sure it’s not a chelator? Sounds fishy.
MA
Marya 11 months ago
Totally agree, it's mainly for preventing oxidation!
YO
Yolando 11 months ago
Sodium metabisulphite is used as an antioxidant in formulations.
PH
Phuong 12 months ago
I remember discussing different roles of excipients, and sodium metabisulphite definitely came up as an antioxidant in some formulations.
LE
Levi 12 months ago
I’m a bit confused. I thought it could also act as a chelator, but now I’m leaning towards antioxidant.
MA
Mabel 12 months ago
I recall a practice question about antioxidants in parenteral formulations, and sodium metabisulphite was listed there too. It seems like the right choice.
SE
Serita 1 year ago
I think sodium metabisulphite is used as an antioxidant, but I'm not completely sure. I remember it being mentioned in class.
DA
Dana 1 year ago
Based on my understanding, sodium metabisulfite is primarily used as an antioxidant in parenteral formulations to prevent degradation of the active ingredient. I think option A is the best answer, but I'll double-check my knowledge just to be sure.
PA
Paola 1 year ago
Wait, I'm a bit confused. Is sodium metabisulfite used as an emulsifier in some cases? I'll need to review my notes to make sure I'm not missing something here.
KI
King 1 year ago
Okay, I remember learning about this in class. Sodium metabisulfite is added to parenteral formulations to prevent oxidation, so it's acting as an antioxidant. I'm confident that A is the correct answer.
CO
Cory 1 year ago
Hmm, I'm not entirely sure about this one. I know sodium metabisulfite has some stabilizing properties, but I can't recall if it's specifically used as a chelator, solubilizer, or cosolvent. I'll have to think this through carefully.
MA
Marguerita 1 year ago
This one seems straightforward. Sodium metabisulfite is commonly used as an antioxidant in parenteral formulations, so I'll go with option A.
BR
Brittney 1 year ago
Sodium metabisulfite? More like sodium 'meta-busy-sulfite' if you ask me. I bet the chemists had a field day coming up with that one!
JE
Jesusa 1 year ago
An emulsifier? Did someone spike the parenteral formulation with a little too much party mix?
CO
Cordelia 1 year ago
↳ replying to Jesusa
D) a cosolvent
JA
Janessa 1 year ago
↳ replying to Jesusa
C) a solubilizer
KA
Kattie 1 year ago
↳ replying to Jesusa
B) a chelator
TO
Tori 1 year ago
↳ replying to Jesusa
A) an antioxidant
KA
Karina 1 year ago
A cosolvent? That's a new one. I think I'll stick with the good old antioxidant option.
EL
Elvera 1 year ago
↳ replying to Karina
Antioxidants are definitely a popular choice for stability in formulations.
DA
Daniela 1 year ago
↳ replying to Karina
I've heard that cosolvents can help improve solubility in some cases.
HE
Herman 1 year ago
↳ replying to Karina
I agree, antioxidants are a safe choice for parenteral formulations.
EL
Eleni 1 year ago
A solubilizer? Nah, that doesn't sound right. This is more of a stabilizing agent, isn't it?
LE
Leatha 1 year ago
Hmm, I'm not sure about that. Isn't a chelator something that binds to metal ions? Seems like a stretch for this question.
RA
Raul 1 year ago
↳ replying to Leatha
C) a solubilizer
JU
Jutta 1 year ago
↳ replying to Leatha
B) a chelator
SH
Shelba 1 year ago
↳ replying to Leatha
A) an antioxidant
GL
Glen 1 year ago
↳ replying to Leatha
C) a solubilizer
MA
Marcos 1 year ago
↳ replying to Leatha
B) a chelator
BO
Bobbye 1 year ago
↳ replying to Leatha
A) an antioxidant
VA
Val 1 year ago
Definitely an antioxidant! Sodium metabisulfite is a common preservative used to prevent oxidation in parenteral formulations.
LA
Launa 1 year ago
↳ replying to Val
No, it is not added as a chelator in parenteral formulations.
TA
Tammara 1 year ago
↳ replying to Val
B) a chelator
MA
Magnolia 1 year ago
↳ replying to Val
Yes, sodium metabisulfite is added as an antioxidant to prevent oxidation.
AN
Andra 1 year ago
↳ replying to Val
A) an antioxidant
TO
Tomoko 2 years ago
I'm not sure about that, I think it could also be used as a chelator to bind metal ions.
FA
Fanny 2 years ago
I agree with Bulah, sodium metabisulphite is commonly used as an antioxidant in parenteral formulations.
BU
Bulah 2 years ago
I think the answer is A) an antioxidant.
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