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NABP FPGEE Exam - Topic 3 Question 113 Discussion

Actual exam question for NABP's FPGEE exam

Question #: 113
Topic #: 3

[All FPGEE Questions]

False statement regarding vitamin D3 metabolism include:

AVitamin C facilitates absorption of vitamin D3 in the liver

BHydroxylation of D3 is in kidney

CHydroxylation of is D3 in the liver

DParathyroid hormone activate metabolism of vitamin D3 in the kidney

ESkin activates synthesis of vitamin D3 by sunlight

Show Suggested Answer

Suggested Answer: B

by Nelida at Nov 19, 2025, 09:15 PM

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Margurite

3 months ago

D is also true. Parathyroid hormone does activate D3 metabolism in the kidney.

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Peggy

3 months ago

E is definitely true. Sunlight is crucial for D3 synthesis.

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Marguerita

3 months ago

I feel like C is misleading. Hydroxylation happens in the kidney, not the liver.

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Rikki

4 months ago

Agreed, A seems off. The liver doesn't need Vitamin C for D3.

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Chi

4 months ago

D is correct, parathyroid hormone plays a big role!

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Terina

4 months ago

E is definitely true, sunlight is key for D3!

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Shantell

5 months ago

Wait, are you sure about C? I thought it was in the liver.

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Mozell

5 months ago

Wait, there's a vitamin D3? I thought it was just called "the sunshine vitamin."

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Ciara

5 months ago

Haha, who needs vitamins when you can just sunbathe all day? Vitamin D3 is overrated anyway.

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Ettie

5 months ago

E is the correct answer. Skin activates the synthesis of vitamin D3 by sunlight.

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Delmy

5 months ago

D is the correct answer. Parathyroid hormone activates the metabolism of vitamin D3 in the kidney.

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Herminia

5 months ago

C is the correct answer. Vitamin D3 is hydroxylated in the liver, not the kidney.

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Ressie

6 months ago

I recall that the skin does synthesize vitamin D3 with sunlight, so E should be true. That leaves us with A or C as possible false statements.

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Coleen

6 months ago

I practiced a question similar to this, and I think parathyroid hormone does play a role in activating vitamin D3 in the kidneys, so D seems correct.

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Jerilyn

6 months ago

I'm not entirely sure, but I feel like vitamin C's role in vitamin D3 metabolism is not really a thing, so A could be the answer.

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Markus

6 months ago

Hmm, I think D is the false statement here. Parathyroid hormone doesn't activate the metabolism of vitamin D3 in the kidney, it's the other way around - the kidney activates vitamin D3 metabolism.

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Geraldine

6 months ago

I'm a bit unsure about this one. I know vitamin D3 metabolism involves the liver and kidneys, but I'm not totally clear on the specifics. I'll have to review my notes before answering.

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Stephanie

6 months ago

I remember learning that the liver is involved in the hydroxylation of vitamin D3, so I think C is the correct answer. The other options seem like they might be false statements.

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Gracia

7 months ago

I think I remember that vitamin D3 is primarily hydroxylated in the liver first, so maybe option C is false?

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Princess

7 months ago

I think A is the false statement. Vitamin C doesn't help with D3 absorption.

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Cecil

7 months ago

Totally agree, D3 hydroxylation happens in the kidney!

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Marleen

7 months ago

No, C is actually true. Hydroxylation in the liver is a step, but not the main one.

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Daniel

7 months ago

A is false, vitamin C doesn't help with D3 absorption.

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Albert

8 months ago

Okay, I'm pretty sure the skin activates the synthesis of vitamin D3 by sunlight, so that rules out E. But the rest of these are a bit confusing.

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Dustin

8 months ago

Hmm, this seems like a tricky one. I'll need to really think through the metabolism of vitamin D3 to get this right.

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Aretha

2 months ago

E is definitely true, sunlight is key!

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Beth

2 months ago

But isn't D true?

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Mose

3 months ago

C seems incorrect too.

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Corinne

3 months ago

I agree, A sounds off.

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Lili

3 months ago

I think A is the false one.

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