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NABP FPGEE Exam - Topic 3 Question 106 Discussion

The side effects of isoniazid are potentialized by deficiency of which vitamin?
B) Pyridoxine
A) Thiamine
C) Folic acid
D) Niacin
E) Cyanocobalamin

NABP FPGEE Exam - Topic 3 Question 106 Discussion

Actual exam question for NABP's FPGEE exam
Question #: 106
Topic #: 3
[All FPGEE Questions]

The side effects of isoniazid are potentialized by deficiency of which vitamin?

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Suggested Answer: B

by Marcelle at Jun 14, 2025, 08:37 AM

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Kelvin
7 months ago
I thought it was thiamine at first, but B makes sense.
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Lucia
7 months ago
Wait, is it really just B? I thought it could be others too.
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Brice
7 months ago
Totally agree, I've read that too!
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Rosita
7 months ago
It's pyridoxine (B) that gets affected by isoniazid.
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Sherron
7 months ago
Yep, B is the one! Super important for nerve health.
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Shoshana
8 months ago
I’m really unsure about this one. I thought it was folic acid, but now I’m second-guessing myself.
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Huey
8 months ago
I practiced a question like this before, and I think it was about pyridoxine being important for preventing neuropathy with isoniazid.
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Marla
8 months ago
I remember something about thiamine and its role in drug metabolism, but I’m not sure if it’s related to isoniazid.
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Alesia
8 months ago
I think isoniazid affects vitamin B6 levels, so I’m leaning towards pyridoxine.
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Tayna
9 months ago
I'm a little confused on this one. I know isoniazid can cause some nasty side effects, but I'm not sure which vitamin deficiency is specifically involved. I'll have to review my pharmacology notes to refresh my memory.
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Renay
9 months ago
Ah, I remember learning about this in class. The side effects of isoniazid are potentiated by a deficiency in pyridoxine, or vitamin B6. I'm confident that's the right answer.
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Erick
9 months ago
Okay, let me see. Isoniazid is an anti-tuberculosis drug, and vitamin deficiencies can affect its metabolism. I think the key is to remember which vitamin is involved in the metabolism of isoniazid.
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Janet
9 months ago
Hmm, I'm a bit unsure about this one. I'll have to think it through carefully and review my notes on isoniazid side effects and vitamin deficiencies.
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Amie
9 months ago
I'm pretty sure the answer is B. Pyridoxine deficiency is known to potentiate the side effects of isoniazid.
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Scarlet
1 year ago
I'm not sure, but I think it's D) Niacin because it's also important for metabolism.
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Olive
1 year ago
I agree with Nobuko, Pyridoxine helps with isoniazid side effects.
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Stefany
1 year ago
Pyridoxine, no doubt. I'd be as lost as a goose without vitamin B6 if I took isoniazid!
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Ben
1 year ago
Ah, the classic isoniazid-pyridoxine interplay. It's like a dance of drug-nutrient interactions, but I've got the moves down.
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Thad
12 months ago
C) Folic acid
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Stephania
1 year ago
B) Pyridoxine
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Mitsue
1 year ago
A) Thiamine
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Margot
1 year ago
Pyridoxine, definitely. I remember learning about how isoniazid can interfere with vitamin B6 metabolism. A classic side effect to watch out for.
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Dacia
1 year ago
Hmm, this one's tricky. I'm leaning towards B, but I'll have to double-check my notes just to be sure.
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Melissia
1 year ago
I'm pretty sure it's pyridoxine, or vitamin B6. Isoniazid is known to deplete this important cofactor.
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Janna
11 months ago
Definitely, it's crucial to prevent any potential side effects.
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Vicente
11 months ago
So it's important to supplement with vitamin B6 when taking isoniazid.
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Wilda
12 months ago
Yes, that's correct. It's important to monitor for deficiency and supplement if necessary.
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Wilda
1 year ago
Yes, that's correct. Isoniazid can lead to pyridoxine deficiency.
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Cora
1 year ago
I think you're right, pyridoxine is the vitamin that is depleted by isoniazid.
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Wendell
1 year ago
I think you're right, pyridoxine is the vitamin that is depleted by isoniazid.
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Nobuko
1 year ago
I think the answer is B) Pyridoxine.
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