NABP FPGEE Exam - Topic 1 Question 83 Discussion

Actual exam question for NABP's FPGEE exam

Question #: 83
Topic #: 1

[All FPGEE Questions]

Which Cytochrome P450 isozyme does not participate appreciably in drug metabolism?

ACYP1A2

BCYP2C9

CCYP3A4

DCYP51

EAll are drug metabolizing isoforms

Show Suggested Answer

Suggested Answer: C

by Sheridan at Jun 02, 2024, 11:55 PM

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Lenna

6 months ago

All of them? Nah, that's misleading.

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Isreal

6 months ago

Definitely, CYP3A4 is the big player in drug metabolism!

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Laurene

6 months ago

Wait, are you sure about CYP51? I thought it had some role.

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Whitley

7 months ago

Totally agree, CYP51 is more about cholesterol synthesis.

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Ruthann

7 months ago

CYP51 doesn't really do drug metabolism.

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Ahmed

7 months ago

All of these isoforms seem to be involved in drug metabolism, but CYP51 stands out as the odd one out.

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Charlesetta

7 months ago

I feel like I've seen a question about CYP2C9 before, but I can't recall if it was about metabolism or something else.

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Tayna

7 months ago

I remember studying that CYP3A4 is a major player in drug metabolism, so it can't be the answer.

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Nada

8 months ago

I think CYP51 is the one that doesn't really get involved in drug metabolism, but I'm not entirely sure.

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Charlene

8 months ago

I'm feeling pretty confident about this one. CYP51 is involved in sterol biosynthesis, not drug metabolism, so that's got to be the answer.

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Justine

8 months ago

Okay, let me review what I know about these isoforms. CYP1A2, CYP2C9, and CYP3A4 are major players in drug metabolism, so I think the answer has to be CYP51.

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Marg

8 months ago

CYP3A4 is the big one for drug metabolism, so I'm guessing that's not the answer. I'll eliminate that one and see what's left.

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Abraham

8 months ago

Hmm, this is a tricky one. I'll need to think through the different Cytochrome P450 isoforms and their primary functions to figure this out.

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Elenore

8 months ago

I'm pretty sure CYP51 is the one that doesn't participate much in drug metabolism, since it's more involved in cholesterol biosynthesis.

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Arlyne

8 months ago

I'm a bit confused on this one. Does the latitude of origin being less negative mean the map is shifted north or south? I'll have to review my notes on map projections.

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Tawna

8 months ago

I'm not sure about the "Use Azure Private IP Address" option. Does that have any relevance to the on-premises network connecting to the route-based GW1? I'll need to research that a bit more.

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Lonny

8 months ago

I remember that with 'rpc' style, the root element would take on the operation name, which doesn't match what we need for 'employeeHours'.

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Emiko

1 year ago

CYP51, the hipster of the P450 world. It's probably too good for drug metabolism, prefers to work on more 'artisanal' processes.

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Melissia

11 months ago

Yeah, CYP51 is too unique to be bothered with drug metabolism.

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Angella

12 months ago

I heard CYP51 is like the cool kid who doesn't follow the crowd.

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Donte

12 months ago

CYP51 is definitely the rebel of the group.

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Kristofer

1 year ago

Hmm, CYP51 doesn't sound like a drug metabolizer to me. Maybe it's just the slacker of the bunch, letting the other isoforms do all the heavy lifting.

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