NABP Exam FPGEE Topic 1 Question 83 Discussion

Actual exam question for NABP's FPGEE exam

Question #: 83
Topic #: 1

[All FPGEE Questions]

Which Cytochrome P450 isozyme does not participate appreciably in drug metabolism?

ACYP1A2

BCYP2C9

CCYP3A4

DCYP51

EAll are drug metabolizing isoforms

Show Suggested Answer

Suggested Answer: C

by Sheridan at Jun 02, 2024, 11:55 PM

Limited Time Offer

25%

Off

Get Premium FPGEE Questions as Interactive Web-Based Practice Test or PDF

Contribute your Thoughts:

Submit Cancel

Emiko

2 months ago

CYP51, the hipster of the P450 world. It's probably too good for drug metabolism, prefers to work on more 'artisanal' processes.

upvoted 0 times

Melissia

17 days ago

Yeah, CYP51 is too unique to be bothered with drug metabolism.

upvoted 0 times

...

Angella

21 days ago

I heard CYP51 is like the cool kid who doesn't follow the crowd.

upvoted 0 times

...

Donte

27 days ago

CYP51 is definitely the rebel of the group.

upvoted 0 times

...

Kristofer

2 months ago

Hmm, CYP51 doesn't sound like a drug metabolizer to me. Maybe it's just the slacker of the bunch, letting the other isoforms do all the heavy lifting.

upvoted 0 times

Rasheeda

30 days ago

Exactly, they are the main drug metabolizing isoforms in the body.

upvoted 0 times

...

Salena

1 months ago

So, the other isoforms like CYP1A2, CYP2C9, and CYP3A4 are the ones doing most of the work.

upvoted 0 times

...

Merissa

1 months ago

Yeah, it's more involved in cholesterol biosynthesis rather than drug metabolism.

upvoted 0 times

...

Veronica

2 months ago

I think you're right, CYP51 is not a major player in drug metabolism.

upvoted 0 times

...

Markus

2 months ago

Ah, CYP51, the black sheep of the P450 family. Probably spends its time playing video games instead of doing actual work.

upvoted 0 times

Meghann

2 months ago

Yeah, probably too busy gaming to metabolize any drugs.

upvoted 0 times

...

Aleisha

2 months ago

I heard CYP51 is the lazy one in the family.

upvoted 0 times

...

Idella

3 months ago

CYP51? Isn't that the one that turns cholesterol into vitamin D? I'm pretty sure that's not a drug metabolizer.

upvoted 0 times

Mammie

2 months ago

Exactly, CYP51 is not a drug metabolizing isoform like the others listed.

upvoted 0 times

...

Gladys

2 months ago

So the answer would be D) CYP51, as it does not participate appreciably in drug metabolism.

upvoted 0 times

...

Daniela

2 months ago

That's right, CYP51 is responsible for converting cholesterol into vitamin D.

upvoted 0 times

...

Belen

2 months ago

Yes, you're correct. CYP51 is not involved in drug metabolism.

upvoted 0 times

...

Lourdes

3 months ago

I'm not sure, but I think E) All are drug metabolizing isoforms.

upvoted 0 times

...

Shawnta

3 months ago

I agree with Rosio, CYP51 is not involved in drug metabolism.

upvoted 0 times

...

Rosio

3 months ago

I think the answer is D) CYP51.

upvoted 0 times

...