NABP FPGEE Exam - Topic 3 Question 118 Discussion

Actual exam question for NABP's FPGEE exam

Question #: 118
Topic #: 3

[All FPGEE Questions]

When evaluating patients with angina for possible development of nitrate tolerance, true statements include:

I tolerance is rarely associated with isosorbide dinitrate.

II tolerance does not occur in patients who are concurrently on

metoprolol.

III tolerance is dependent upon the administration schedule of nitrate medication.

AI only

BIII only

CI and II only

DII and III only

EI, II and III

Show Suggested Answer

Suggested Answer: B

by Reena at Apr 13, 2026, 02:46 AM

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Lezlie

18 days ago

Totally agree, the schedule really matters for tolerance!

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Alana

23 days ago

I thought tolerance was common with isosorbide dinitrate.

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Edison

1 month ago

I’m leaning towards option B because I think tolerance is mostly about how you take the medication, but I’m not entirely confident.

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Milly

1 month ago

I feel like we talked about the importance of the administration schedule for nitrates affecting tolerance. That might be key here.

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Jodi

2 months ago

I think we practiced a question about tolerance and beta-blockers, but I can't recall if metoprolol completely prevents it.

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Kris

2 months ago

I remember discussing nitrate tolerance in class, but I'm not sure if isosorbide dinitrate is really that different from other nitrates.

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